The volatile oil from Acori Graminei Rhizoma downregulates NMDARs-ERK1/2-CREB signaling pathway to alleviate pain related emotions induced by inflammatory pain in rats

The volatile oil from Acori Graminei Rhizoma downregulates NMDARs-ERK1/2-CREB signaling pathway to alleviate pain related emotions induced by inflammatory pain in rats

Objective: To investigate whether Acori Graminei Rhizoma (AGR) volatile oil can reduce inflammatory pain-induced pain-related mood in rats by downregulating NMDARs-ERK 1/2-CREB signaling pathway. Methods: Thirty-six male SD rats were randomly divided into six groups: control group, sham group, compl...

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Bibliographic Details
Main Authors: Shiqi LI, Cuizhu YANG, Runheng ZHANG, Shuhan WANG, Yaqi YANG, Jing LIU, Guoying LI, Yuxin MA
Format: Article
Language:English
Published: KeAi Communications Co., Ltd. 2023-03-01
Series:Journal of Holistic Integrative Pharmacy
Subjects:
Inflammatory pain
Pain-related emotions
NMDAR
ERK
CREB
Online Access:http://www.sciencedirect.com/science/article/pii/S2707368823000948
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