Ionizing radiation effects on osseointegration: a pre-clinical study

The purpose of this study was to evaluate the effect of a single dose of ionizing radiation (30 Gy) on the osseointegration of implants in the rabbit tibia. Twenty rabbits received two dental Morse-tapered junction implants and one implant in each tibia. The animals were randomly divided into two gr...

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Main Authors: Roberta de Oliveira Alves, Guilheme José Pimentel Lopes de Oliveira, Rita Catarina de Oliveira, Pedro Henrique Justino Oliveira Limirio, Marcela Claudino, Darceny Zanetta-Barbosa, Priscilla Ferreira Barbosa Soares
Format: Article
Language:English
Published: Sociedade Brasileira de Pesquisa Odontológica 2024-12-01
Series:Brazilian Oral Research
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Online Access:http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1806-83242024000110000&lng=en&tlng=en
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Summary:The purpose of this study was to evaluate the effect of a single dose of ionizing radiation (30 Gy) on the osseointegration of implants in the rabbit tibia. Twenty rabbits received two dental Morse-tapered junction implants and one implant in each tibia. The animals were randomly divided into two groups (n=10), non-irradiated (NoIr) and irradiated (Ir), wherein the Ir group received a single dose of 30 Gy radiation 2 weeks after implant installation. Microtomographic analyses (BV/TV) and histomorphometric assessments (BIC and BABT) were performed 4 weeks after implant installation. One-way ANOVA, Tukey's test, and Student's t-test (α=0.05) were used for data analysis. The results showed that BV/TV did not differ significantly between the Ir and NoIr groups (P = 0.071). In the histomorphometric analysis, neither BIC nor BABT showed significant differences between the NoIr and Ir groups (p>0.05). In conclusion, ionizing radiation in dental implants does not appear to interfere with osseointegration when installed prior to irradiation.
ISSN:1807-3107