Urinary Salmonella Enteritis carriage in a patient living with HIV
BACKGROUND: Non-typhoidal Salmonella(NTS) cause asymptomatic carriage in the gastrointestinal tract and rarely in the urinary tract after infections, especially in patients with predisposing factors. When the rates of quinolone-resistant Salmonella spp. are increasing rapidly, the implementation of...
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| Main Authors: | , , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
Elsevier
2024-12-01
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| Series: | Journal of Global Antimicrobial Resistance |
| Subjects: | |
| Online Access: | http://www.sciencedirect.com/science/article/pii/S2213716524003904 |
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| Summary: | BACKGROUND: Non-typhoidal Salmonella(NTS) cause asymptomatic carriage in the gastrointestinal tract and rarely in the urinary tract after infections, especially in patients with predisposing factors. When the rates of quinolone-resistant Salmonella spp. are increasing rapidly, the implementation of the correct treatment protocol in patients in the risk group is the most fundamental step to prevent the development of carriage. Here, we report a patient who developed urinary carriage of S.Enteritidis and was living with HIV. CASE: A 57-year-old male patient living with HIV and various comorbidities was admitted to the hospital with the complaint of dysuria. Ciprofloxacin-resistant S.Enteritidis was grown in the urine culture. Urinary tract infection(UTI) was considered and five-day cefixime treatment was started. The patient's symptoms persisted and the growth continued in the urine culture taken again. S.Enteritidis was not grown in the stool culture of the patient. The patient was given cefixime treatment for two more weeks and there was no growth in follow-up cultures. Isolates grown in the urine cultures of the patient for 27 months were found to be of the same genotype by AP-PCR(Figure). DISCUSSION: When NTS-induced UTI is detected, patients should be evaluated for the presence of risk factors. In the presence of risk factors, even long-term antibiotic treatment may be insufficient to ensure full recovery and prevent carriage. Increasing rates of resistance to fluoroquinolones, which are commonly used to treat salmonella, are alarming and require rigorous regulation of antimicrobial use policies. Monitoring NTS infections and potential carriage in patients living with HIV is vital. |
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| ISSN: | 2213-7165 |