Fluorodeoxyglucose-positron emission tomography integrated with computed tomography in suspected recurrent cervical cancer

Carcinoma of the uterine cervix represents the fourth most common malignant tumor and the fourth leading cause of mortality from cancer in females, and approximately one third of women with cervical carcinoma diagnosis will develop relapse. In follow-up and suspicion of recurrence of cervical cancer...

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Main Authors: Stojiljković Milica, Artiko Vera
Format: Article
Language:English
Published: University of Belgrade, Medical Faculty 2024-01-01
Series:Medicinski Podmladak
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Online Access:https://scindeks-clanci.ceon.rs/data/pdf/0369-1527/2024/0369-15272403009S.pdf
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author Stojiljković Milica
Artiko Vera
author_facet Stojiljković Milica
Artiko Vera
author_sort Stojiljković Milica
collection DOAJ
description Carcinoma of the uterine cervix represents the fourth most common malignant tumor and the fourth leading cause of mortality from cancer in females, and approximately one third of women with cervical carcinoma diagnosis will develop relapse. In follow-up and suspicion of recurrence of cervical cancer, various imaging modalities such as computed tomography (CT), magnetic resonance imaging (MRI) and positron emission tomography/computed tomography (PET/CT) can be used. However, the role of PET/CT is constantly increasing in these patients and the latest National Comprehensive Cancer Network (NCCN) guideline Version 1.2023 recommends PET/CT as the imaging method of choice in follow-up of patients with disease stage II or higher, and in suspicion of recurrent or metastatic disease. PET/ CT shows higher sensitivity and specificity than conventional imaging in suspected recurrent cervical cancer, particularly in the evaluation of distant recurrent sites. An additional benefit of PET/CT in these patients is its impact on treatment management in approximately half of them. Also, PET/CT has a prognostic role in progression-free and overall survival, and patients with positive PET/CT for recurrence have significantly worse prognosis.
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institution Kabale University
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spelling doaj-art-e6b96ea2440441d8bf4fa3f91abdbda42024-12-02T12:54:27ZengUniversity of Belgrade, Medical FacultyMedicinski Podmladak0369-15272466-55252024-01-0175391310.5937/mp75-428670369-15272403009SFluorodeoxyglucose-positron emission tomography integrated with computed tomography in suspected recurrent cervical cancerStojiljković Milica0https://orcid.org/0000-0001-7170-4433Artiko Vera1https://orcid.org/0000-0002-6078-4500Univerzitet u Beogradu, Medicinski fakultet, Beograd, SerbiaUniverzitet u Beogradu, Medicinski fakultet, Beograd, SerbiaCarcinoma of the uterine cervix represents the fourth most common malignant tumor and the fourth leading cause of mortality from cancer in females, and approximately one third of women with cervical carcinoma diagnosis will develop relapse. In follow-up and suspicion of recurrence of cervical cancer, various imaging modalities such as computed tomography (CT), magnetic resonance imaging (MRI) and positron emission tomography/computed tomography (PET/CT) can be used. However, the role of PET/CT is constantly increasing in these patients and the latest National Comprehensive Cancer Network (NCCN) guideline Version 1.2023 recommends PET/CT as the imaging method of choice in follow-up of patients with disease stage II or higher, and in suspicion of recurrent or metastatic disease. PET/ CT shows higher sensitivity and specificity than conventional imaging in suspected recurrent cervical cancer, particularly in the evaluation of distant recurrent sites. An additional benefit of PET/CT in these patients is its impact on treatment management in approximately half of them. Also, PET/CT has a prognostic role in progression-free and overall survival, and patients with positive PET/CT for recurrence have significantly worse prognosis.https://scindeks-clanci.ceon.rs/data/pdf/0369-1527/2024/0369-15272403009S.pdfcervical cancerclinical impactconventional imagingpositron emission tomography/computed tomographyprognosisrecurrence
spellingShingle Stojiljković Milica
Artiko Vera
Fluorodeoxyglucose-positron emission tomography integrated with computed tomography in suspected recurrent cervical cancer
Medicinski Podmladak
cervical cancer
clinical impact
conventional imaging
positron emission tomography/computed tomography
prognosis
recurrence
title Fluorodeoxyglucose-positron emission tomography integrated with computed tomography in suspected recurrent cervical cancer
title_full Fluorodeoxyglucose-positron emission tomography integrated with computed tomography in suspected recurrent cervical cancer
title_fullStr Fluorodeoxyglucose-positron emission tomography integrated with computed tomography in suspected recurrent cervical cancer
title_full_unstemmed Fluorodeoxyglucose-positron emission tomography integrated with computed tomography in suspected recurrent cervical cancer
title_short Fluorodeoxyglucose-positron emission tomography integrated with computed tomography in suspected recurrent cervical cancer
title_sort fluorodeoxyglucose positron emission tomography integrated with computed tomography in suspected recurrent cervical cancer
topic cervical cancer
clinical impact
conventional imaging
positron emission tomography/computed tomography
prognosis
recurrence
url https://scindeks-clanci.ceon.rs/data/pdf/0369-1527/2024/0369-15272403009S.pdf
work_keys_str_mv AT stojiljkovicmilica fluorodeoxyglucosepositronemissiontomographyintegratedwithcomputedtomographyinsuspectedrecurrentcervicalcancer
AT artikovera fluorodeoxyglucosepositronemissiontomographyintegratedwithcomputedtomographyinsuspectedrecurrentcervicalcancer