Reduction in mitochondrial iron alleviates cardiac damage during injury
Abstract Excess cellular iron increases reactive oxygen species (ROS) production and causes cellular damage. Mitochondria are the major site of iron metabolism and ROS production; however, few studies have investigated the role of mitochondrial iron in the development of cardiac disorders, such as i...
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| Main Authors: | Hsiang‐Chun Chang, Rongxue Wu, Meng Shang, Tatsuya Sato, Chunlei Chen, Jason S Shapiro, Ting Liu, Anita Thakur, Konrad T Sawicki, Sathyamangla VN Prasad, Hossein Ardehali |
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| Format: | Article |
| Language: | English |
| Published: |
Springer Nature
2016-02-01
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| Series: | EMBO Molecular Medicine |
| Subjects: | |
| Online Access: | https://doi.org/10.15252/emmm.201505748 |
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