Sex differences in exercise‐induced arterial hypoxemia and pulmonary edema following high‐intensity exercise in highly trained endurance athletes
Abstract This study investigated sex differences in the development of pulmonary edema and exercise‐induced arterial hypoxemia (EIAH) in well‐trained endurance athletes during near‐maximal exercise in a real‐world setting. Twenty participants (10M vs. 10F; V̇O2peak: 69.3 (8.8) vs. 50.7 (4.1) ml∙kg−1...
Saved in:
| Main Authors: | , , , , , , , , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Wiley
2025-01-01
|
| Series: | Physiological Reports |
| Subjects: | |
| Online Access: | https://doi.org/10.14814/phy2.70190 |
| Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
| _version_ | 1841527546626179072 |
|---|---|
| author | Alanna S. Hind Reid A. Mitchell Olivia N. Ferguson Morgan Flynn Satvir S. Dhillon Karine Badra Kathryn M. Milne Danilo Iannetta Michael S. Koehle Jordan A. Guenette |
| author_facet | Alanna S. Hind Reid A. Mitchell Olivia N. Ferguson Morgan Flynn Satvir S. Dhillon Karine Badra Kathryn M. Milne Danilo Iannetta Michael S. Koehle Jordan A. Guenette |
| author_sort | Alanna S. Hind |
| collection | DOAJ |
| description | Abstract This study investigated sex differences in the development of pulmonary edema and exercise‐induced arterial hypoxemia (EIAH) in well‐trained endurance athletes during near‐maximal exercise in a real‐world setting. Twenty participants (10M vs. 10F; V̇O2peak: 69.3 (8.8) vs. 50.7 (4.1) ml∙kg−1∙min−1) underwent a maximal incremental treadmill test (visit 1) and a time trial on a steep trail (~2.5 km, ~800 m elevation gain) in North Vancouver (visit 2). Pulmonary edema was evaluated using handheld lung ultrasound ~10–15 min post‐exercise and oxygen saturation (SpO2) was monitored using finger pulse oximetry. Males completed the time trial significantly faster than females (M: 31.5 (6.5) vs. F: 40.4 (7.5) min, p = 0.006), while females sustained a higher percentage of their visit 1 heart rate (M: 94 (1) vs. F: 96 (1) %max, p = 0.02). All participants developed EIAH, with no sex differences in end‐exercise SpO2 (M: 89 (4) % vs. F: 90 (3) %, respectively, p = 0.35). There was no evidence of pulmonary edema, assessed through ultrasound b‐line scores, with no differences between sexes (M: 0.3 (1.0) vs. F: 0.5 (1.5), respectively, p = 0.60). Pulmonary edema is an unlikely contributor to EIAH in endurance athletes performing near‐maximal time trial exercise in a real‐world setting. |
| format | Article |
| id | doaj-art-e6829d46a08a48c7863f10947ca4295f |
| institution | Kabale University |
| issn | 2051-817X |
| language | English |
| publishDate | 2025-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | Physiological Reports |
| spelling | doaj-art-e6829d46a08a48c7863f10947ca4295f2025-01-15T13:36:31ZengWileyPhysiological Reports2051-817X2025-01-01131n/an/a10.14814/phy2.70190Sex differences in exercise‐induced arterial hypoxemia and pulmonary edema following high‐intensity exercise in highly trained endurance athletesAlanna S. Hind0Reid A. Mitchell1Olivia N. Ferguson2Morgan Flynn3Satvir S. Dhillon4Karine Badra5Kathryn M. Milne6Danilo Iannetta7Michael S. Koehle8Jordan A. Guenette9Centre for Heart Lung Innovation The University of British Columbia (UBC) and St. Paul's Hospital (SPH) Vancouver British Columbia CanadaCentre for Heart Lung Innovation The University of British Columbia (UBC) and St. Paul's Hospital (SPH) Vancouver British Columbia CanadaCentre for Heart Lung Innovation The University of British Columbia (UBC) and St. Paul's Hospital (SPH) Vancouver British Columbia CanadaCentre for Heart Lung Innovation The University of British Columbia (UBC) and St. Paul's Hospital (SPH) Vancouver British Columbia CanadaCentre for Heart Lung Innovation The University of British Columbia (UBC) and St. Paul's Hospital (SPH) Vancouver British Columbia CanadaDepartment of Emergency Medicine SPH Vancouver British Columbia CanadaCentre for Heart Lung Innovation The University of British Columbia (UBC) and St. Paul's Hospital (SPH) Vancouver British Columbia CanadaDepartment of Anesthesiology, School of Medicine University of Utah Salt Lake City Utah USASchool of Kinesiology UBC Vancouver British Columbia CanadaCentre for Heart Lung Innovation The University of British Columbia (UBC) and St. Paul's Hospital (SPH) Vancouver British Columbia CanadaAbstract This study investigated sex differences in the development of pulmonary edema and exercise‐induced arterial hypoxemia (EIAH) in well‐trained endurance athletes during near‐maximal exercise in a real‐world setting. Twenty participants (10M vs. 10F; V̇O2peak: 69.3 (8.8) vs. 50.7 (4.1) ml∙kg−1∙min−1) underwent a maximal incremental treadmill test (visit 1) and a time trial on a steep trail (~2.5 km, ~800 m elevation gain) in North Vancouver (visit 2). Pulmonary edema was evaluated using handheld lung ultrasound ~10–15 min post‐exercise and oxygen saturation (SpO2) was monitored using finger pulse oximetry. Males completed the time trial significantly faster than females (M: 31.5 (6.5) vs. F: 40.4 (7.5) min, p = 0.006), while females sustained a higher percentage of their visit 1 heart rate (M: 94 (1) vs. F: 96 (1) %max, p = 0.02). All participants developed EIAH, with no sex differences in end‐exercise SpO2 (M: 89 (4) % vs. F: 90 (3) %, respectively, p = 0.35). There was no evidence of pulmonary edema, assessed through ultrasound b‐line scores, with no differences between sexes (M: 0.3 (1.0) vs. F: 0.5 (1.5), respectively, p = 0.60). Pulmonary edema is an unlikely contributor to EIAH in endurance athletes performing near‐maximal time trial exercise in a real‐world setting.https://doi.org/10.14814/phy2.70190arterial hypoxemiab‐linesexercise physiologypulmonary edemarespiratory physiologyultrasound |
| spellingShingle | Alanna S. Hind Reid A. Mitchell Olivia N. Ferguson Morgan Flynn Satvir S. Dhillon Karine Badra Kathryn M. Milne Danilo Iannetta Michael S. Koehle Jordan A. Guenette Sex differences in exercise‐induced arterial hypoxemia and pulmonary edema following high‐intensity exercise in highly trained endurance athletes Physiological Reports arterial hypoxemia b‐lines exercise physiology pulmonary edema respiratory physiology ultrasound |
| title | Sex differences in exercise‐induced arterial hypoxemia and pulmonary edema following high‐intensity exercise in highly trained endurance athletes |
| title_full | Sex differences in exercise‐induced arterial hypoxemia and pulmonary edema following high‐intensity exercise in highly trained endurance athletes |
| title_fullStr | Sex differences in exercise‐induced arterial hypoxemia and pulmonary edema following high‐intensity exercise in highly trained endurance athletes |
| title_full_unstemmed | Sex differences in exercise‐induced arterial hypoxemia and pulmonary edema following high‐intensity exercise in highly trained endurance athletes |
| title_short | Sex differences in exercise‐induced arterial hypoxemia and pulmonary edema following high‐intensity exercise in highly trained endurance athletes |
| title_sort | sex differences in exercise induced arterial hypoxemia and pulmonary edema following high intensity exercise in highly trained endurance athletes |
| topic | arterial hypoxemia b‐lines exercise physiology pulmonary edema respiratory physiology ultrasound |
| url | https://doi.org/10.14814/phy2.70190 |
| work_keys_str_mv | AT alannashind sexdifferencesinexerciseinducedarterialhypoxemiaandpulmonaryedemafollowinghighintensityexerciseinhighlytrainedenduranceathletes AT reidamitchell sexdifferencesinexerciseinducedarterialhypoxemiaandpulmonaryedemafollowinghighintensityexerciseinhighlytrainedenduranceathletes AT olivianferguson sexdifferencesinexerciseinducedarterialhypoxemiaandpulmonaryedemafollowinghighintensityexerciseinhighlytrainedenduranceathletes AT morganflynn sexdifferencesinexerciseinducedarterialhypoxemiaandpulmonaryedemafollowinghighintensityexerciseinhighlytrainedenduranceathletes AT satvirsdhillon sexdifferencesinexerciseinducedarterialhypoxemiaandpulmonaryedemafollowinghighintensityexerciseinhighlytrainedenduranceathletes AT karinebadra sexdifferencesinexerciseinducedarterialhypoxemiaandpulmonaryedemafollowinghighintensityexerciseinhighlytrainedenduranceathletes AT kathrynmmilne sexdifferencesinexerciseinducedarterialhypoxemiaandpulmonaryedemafollowinghighintensityexerciseinhighlytrainedenduranceathletes AT daniloiannetta sexdifferencesinexerciseinducedarterialhypoxemiaandpulmonaryedemafollowinghighintensityexerciseinhighlytrainedenduranceathletes AT michaelskoehle sexdifferencesinexerciseinducedarterialhypoxemiaandpulmonaryedemafollowinghighintensityexerciseinhighlytrainedenduranceathletes AT jordanaguenette sexdifferencesinexerciseinducedarterialhypoxemiaandpulmonaryedemafollowinghighintensityexerciseinhighlytrainedenduranceathletes |