Quercetin regulates phenotypic transformation of vascular smooth muscle cells induced by angiotensin Ⅱ through Nrf2/HO-1 signaling pathway

Quercetin regulates phenotypic transformation of vascular smooth muscle cells induced by angiotensin Ⅱ through Nrf2/HO-1 signaling pathway

ObjectiveTo investigate the protective effect and mechanism of quercetin (QR) against angiotensin Ⅱ (Ang Ⅱ)-induced injury and phenotypic transformation in vascular smooth muscle cells (VSMCs). MethodsVSMCs were treated with Ang Ⅱ and divided into four groups: control (Ctrl), QR control, model (Ang...

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Bibliographic Details
Main Authors: Mamatimin ABDURESHIT, Wei ZHU
Format: Article
Language:English
Published: Shanghai Chinese Clinical Medicine Press Co., Ltd. 2025-08-01
Series:Zhongguo Linchuang Yixue
Subjects:
quercetin
intracranial aneurysm
vascular smooth muscle cell
oxidative stress
phenotypic transformation
nuclearfactor erythroid 2-related factor 2
Online Access:https://www.c-jcm.com/article/doi/10.12025/j.issn.1008-6358.2025.20250453
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https://www.c-jcm.com/article/doi/10.12025/j.issn.1008-6358.2025.20250453

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