A multilevel screening pipeline in zebrafish identifies therapeutic drugs for GAN
Abstract Giant axonal neuropathy (GAN) is a fatal neurodegenerative disorder for which there is currently no treatment. Affecting the nervous system, GAN starts in infancy with motor deficits that rapidly evolve toward total loss of ambulation. Using the gan zebrafish model that reproduces the loss...
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| Main Authors: | Léa Lescouzères, Cédric Hassen‐Khodja, Anaïs Baudot, Benoît Bordignon, Pascale Bomont |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Springer Nature
2023-05-01
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| Series: | EMBO Molecular Medicine |
| Subjects: | |
| Online Access: | https://doi.org/10.15252/emmm.202216267 |
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