EFFICACY OF INFECTIOUS BRONCHITIS DISEASE VACCINES AS MEASURED BY VIRAL SHED AFTER VIRULENT CHALLENGE IN BROILER
Infectious bronchitis threatens the poultry industry throughout the world, The control of IB of the big problems in the world because of the wide variations in serotypes and development in the virulence of strains from time to time, and nature is very contagious, the rapid evolution in the specific...
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| Main Author: | |
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| Format: | Article |
| Language: | English |
| Published: |
College of Veterinary Medicine, University of Basrah, Iraq
2017-12-01
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| Series: | Basrah Journal of Veterinary Research |
| Subjects: | |
| Online Access: | https://bjvr.uobasrah.edu.iq/article_143548_852414363833e479731fbdb2539b8dcb.pdf |
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| Summary: | Infectious bronchitis threatens the poultry industry throughout the world, The
control of IB of the big problems in the world because of the wide variations in
serotypes and development in the virulence of strains from time to time, and nature is
very contagious, the rapid evolution in the specific tissue tropism and recombinants
because of the synchronization of infection with different virus types and the use of
live vaccines.found that the IB virus which is isolated from the recent outbreak is the
same serotype but the difference genotype compared with the strains of current
vaccine. Previous studies have indicated that the broiler vaccination with inactivated
vaccines showed significantly less virus shed if challenge with the homologous
vaccines (same genotype viruses) as compared with birds that vaccination genetically
heterologous vaccines. The current study compared the extent of protection resulting
from vaccination with live Commercial vaccines(Volvac® IB Mass MLV, Poulvac®
IB Primer (D274), Avipro® IB M48 and mixed vaccine from (Volvac®, Poulvac® and
Avipro®)). Vaccinates werechallenged with virulent field isolate (Variant2) strain.
Weekly post-vaccination, collected serum for analytical knowledge of the amount of
antibodies using hemagglutiation inhibition test against all vaccine antigens used in
the experiment after challenge with field virulent (Variant2 isolate), examine the birds
daily to monitor the morbidity and mortality rates in selected periods for shedding
virus by real time PCRto detect and quantitate the IBV viral copy number from
clinical samples.After challenge with (Variant2) birdsvaccinated with mixed vaccine
revealed less shedding virus compared to (Volvac®, Poulvac® and Avipro®)-
vaccinated birdsboth separately.Genotypic differences between the vaccines and the
challenge virus do not reduce the ability of vaccines to protect against the disease, but
genotypic similarities reduce the virus shed and limiting its spread. The use of same249
genetically advanced vaccines and expected to provide the best protection against the
challenge with virulent field IB strains and limit the spread of poultry farming |
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| ISSN: | 1813-8497 2410-8456 |