Peripheral Red Blood Cell Split Chimerism as a Consequence of Intramedullary Selective Apoptosis of Recipient Red Blood Cells in a Case of Sickle Cell Disease

Peripheral Red Blood Cell Split Chimerism as a Consequence of Intramedullary Selective Apoptosis of Recipient Red Blood Cells in a Case of Sickle Cell Disease

Allogeneic cellular gene therapy through hematopoietic stem cell transplantation is the only radical cure for congenital hemoglobinopathies like thalassemia and sickle cell anemia. Persistent mixed hematopoietic chimerism (PMC) has been described in thalassemia and sickle cell anemia. Here, we descr...

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Bibliographic Details
Main Authors: Marco Marziali, Antonella Isgrò, Pietro Sodani, Javid Gaziev, Daniela Fraboni, Katia Paciaroni, Cristiano Gallucci, Cecilia Alfieri, Andrea Roveda, Gioia De Angelis, Luisa Cardarelli, Michela Ribersani, Marco Andreani, Guido Lucarelli
Format: Article
Language:English
Published: PAGEPress Publications 2014-08-01
Series:Mediterranean Journal of Hematology and Infectious Diseases
Subjects:
Sickle Cell Disease
Split Chimeirsm
Bone Marrow
Online Access:http://www.mjhid.org/index.php/mjhid/article/view/2056
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http://www.mjhid.org/index.php/mjhid/article/view/2056

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