TIVelo: RNA velocity estimation leveraging cluster-level trajectory inference

Abstract RNA velocity inference is a valuable tool for understanding cell development, differentiation, and disease progression. However, existing RNA velocity inference methods typically rely on explicit assumptions of ordinary differential equations (ODE), which prohibits them from capturing compl...

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Bibliographic Details
Main Authors: Muyang Ge, Jishuai Miao, Ji Qi, Xiaocheng Zhou, Zhixiang Lin
Format: Article
Language:English
Published: Nature Portfolio 2025-07-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-025-61628-x
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