Evaluation of Demographic, Clinical, and Histological Characteristics of Spitz Nevus Among Iranian Patients: A Retrospective Study From 2016 to 2021
ABSTRACT Background and Aims Spitz nevus is a rare benign tumor classified among unusual melanocytic nevi. This study aimed to identify the demographic, clinical, and histopathological characteristics of Spitz nevus among Iranian patients. Methods This descriptive, retrospective study involved revie...
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2024-12-01
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| Online Access: | https://doi.org/10.1002/hsr2.70274 |
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| author | Zeinab Aryanian Kambiz Kamyab Safoura Shakoei Ifa Etesami Vahidehsadat Azhari Sami Hesami Azadeh Khayyat Parvaneh Hatami |
| author_facet | Zeinab Aryanian Kambiz Kamyab Safoura Shakoei Ifa Etesami Vahidehsadat Azhari Sami Hesami Azadeh Khayyat Parvaneh Hatami |
| author_sort | Zeinab Aryanian |
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| description | ABSTRACT Background and Aims Spitz nevus is a rare benign tumor classified among unusual melanocytic nevi. This study aimed to identify the demographic, clinical, and histopathological characteristics of Spitz nevus among Iranian patients. Methods This descriptive, retrospective study involved reviewing the records of patients diagnosed with Spitz nevus at a referral and academic hospital in Iran between 2016 and 2021. Data were extracted regarding demographic characteristics, including age, gender, location, clinical symptoms, disease duration, medical history, and medication history. Additionally, biopsied lesions were evaluated for histopathological features. Results A total of 86 patients were evaluated, comprising 37 males (43.5%) and 49 females (55.5%). The mean age was 15.6 years (SD ± 14.8). The most common sites of involvement were the upper extremities (23.3%) and face (17.4%). Disease durations of 1 and 2 years were the most prevalent, observed in 24 (27.9%) and 26 patients (30.2%), respectively. Notably, none of the patients had any underlying diseases. Histopathological evaluation revealed compound Spitz nevus in 25 patients (29.4%), junctional Spitz nevus in 14 patients (16.5%), and dermal Spitz nevus in 10 patients (11.8%). Conclusion This study provides a comprehensive overview of the demographics, clinical presentation, and histopathological features of Spitz nevus among Iranian patients, highlighting the necessity for ongoing research and innovation in diagnostic techniques. |
| format | Article |
| id | doaj-art-e61e65d7a6e54cf79c35b9a183e0098f |
| institution | Kabale University |
| issn | 2398-8835 |
| language | English |
| publishDate | 2024-12-01 |
| publisher | Wiley |
| record_format | Article |
| series | Health Science Reports |
| spelling | doaj-art-e61e65d7a6e54cf79c35b9a183e0098f2024-12-30T08:46:34ZengWileyHealth Science Reports2398-88352024-12-01712n/an/a10.1002/hsr2.70274Evaluation of Demographic, Clinical, and Histological Characteristics of Spitz Nevus Among Iranian Patients: A Retrospective Study From 2016 to 2021Zeinab Aryanian0Kambiz Kamyab1Safoura Shakoei2Ifa Etesami3Vahidehsadat Azhari4Sami Hesami5Azadeh Khayyat6Parvaneh Hatami7Autoimmune Bullous Diseases Research Center Tehran University of Medical Sciences Tehran IranDepartment of Dermatopatholology, Razi Hospital Tehran University of Medical Sciences Tehran IranDermatology Department of Imam Khomeini Complex Hospital Tehran University of Medical Sciences Tehran IranAutoimmune Bullous Diseases Research Center Tehran University of Medical Sciences Tehran IranDepartment of Dermatopatholology, Razi Hospital Tehran University of Medical Sciences Tehran IranAutoimmune Bullous Diseases Research Center Tehran University of Medical Sciences Tehran IranPathology Department of Medical College of Wisconsin Milwaukee Wisconsin USAAutoimmune Bullous Diseases Research Center Tehran University of Medical Sciences Tehran IranABSTRACT Background and Aims Spitz nevus is a rare benign tumor classified among unusual melanocytic nevi. This study aimed to identify the demographic, clinical, and histopathological characteristics of Spitz nevus among Iranian patients. Methods This descriptive, retrospective study involved reviewing the records of patients diagnosed with Spitz nevus at a referral and academic hospital in Iran between 2016 and 2021. Data were extracted regarding demographic characteristics, including age, gender, location, clinical symptoms, disease duration, medical history, and medication history. Additionally, biopsied lesions were evaluated for histopathological features. Results A total of 86 patients were evaluated, comprising 37 males (43.5%) and 49 females (55.5%). The mean age was 15.6 years (SD ± 14.8). The most common sites of involvement were the upper extremities (23.3%) and face (17.4%). Disease durations of 1 and 2 years were the most prevalent, observed in 24 (27.9%) and 26 patients (30.2%), respectively. Notably, none of the patients had any underlying diseases. Histopathological evaluation revealed compound Spitz nevus in 25 patients (29.4%), junctional Spitz nevus in 14 patients (16.5%), and dermal Spitz nevus in 10 patients (11.8%). Conclusion This study provides a comprehensive overview of the demographics, clinical presentation, and histopathological features of Spitz nevus among Iranian patients, highlighting the necessity for ongoing research and innovation in diagnostic techniques.https://doi.org/10.1002/hsr2.70274clinicaldemographicspathologySpitz nevus |
| spellingShingle | Zeinab Aryanian Kambiz Kamyab Safoura Shakoei Ifa Etesami Vahidehsadat Azhari Sami Hesami Azadeh Khayyat Parvaneh Hatami Evaluation of Demographic, Clinical, and Histological Characteristics of Spitz Nevus Among Iranian Patients: A Retrospective Study From 2016 to 2021 Health Science Reports clinical demographics pathology Spitz nevus |
| title | Evaluation of Demographic, Clinical, and Histological Characteristics of Spitz Nevus Among Iranian Patients: A Retrospective Study From 2016 to 2021 |
| title_full | Evaluation of Demographic, Clinical, and Histological Characteristics of Spitz Nevus Among Iranian Patients: A Retrospective Study From 2016 to 2021 |
| title_fullStr | Evaluation of Demographic, Clinical, and Histological Characteristics of Spitz Nevus Among Iranian Patients: A Retrospective Study From 2016 to 2021 |
| title_full_unstemmed | Evaluation of Demographic, Clinical, and Histological Characteristics of Spitz Nevus Among Iranian Patients: A Retrospective Study From 2016 to 2021 |
| title_short | Evaluation of Demographic, Clinical, and Histological Characteristics of Spitz Nevus Among Iranian Patients: A Retrospective Study From 2016 to 2021 |
| title_sort | evaluation of demographic clinical and histological characteristics of spitz nevus among iranian patients a retrospective study from 2016 to 2021 |
| topic | clinical demographics pathology Spitz nevus |
| url | https://doi.org/10.1002/hsr2.70274 |
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