Molecular tipping points in plant cell surface H+ homeostasis and signalling

Hydrogen, a deceptively simple element, plays crucial roles in regulating life on Earth. The concentration of hydrogen ions (H+) determines the pH of biological systems and dictates virtually all biochemical processes. The pH modulates the structure, physicochemical properties and function of most m...

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Main Authors: Kaltra Xhelilaj, Anja Thoe Fuglsang, Julien Gronnier, Michael Palmgren
Format: Article
Language:English
Published: Cambridge University Press 2025-01-01
Series:Quantitative Plant Biology
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Online Access:https://www.cambridge.org/core/product/identifier/S2632882825100027/type/journal_article
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author Kaltra Xhelilaj
Anja Thoe Fuglsang
Julien Gronnier
Michael Palmgren
author_facet Kaltra Xhelilaj
Anja Thoe Fuglsang
Julien Gronnier
Michael Palmgren
author_sort Kaltra Xhelilaj
collection DOAJ
description Hydrogen, a deceptively simple element, plays crucial roles in regulating life on Earth. The concentration of hydrogen ions (H+) determines the pH of biological systems and dictates virtually all biochemical processes. The pH modulates the structure, physicochemical properties and function of most macromolecules. The plant cell surface is characterized by tremendous variations in apoplastic pH, serving as informative signals shaping plant development and its interaction with the environment. Here, we discuss the principles underlying cell surface H+ homeostasis, the molecular tipping points that regulate fast, controlled and informative changes in apoplastic pH, as well as open questions regarding the regulation of plasma membrane H+-ATPases.
format Article
id doaj-art-e5c937d0cb6d4c79976b4dc82df78f4f
institution Kabale University
issn 2632-8828
language English
publishDate 2025-01-01
publisher Cambridge University Press
record_format Article
series Quantitative Plant Biology
spelling doaj-art-e5c937d0cb6d4c79976b4dc82df78f4f2025-08-26T11:45:22ZengCambridge University PressQuantitative Plant Biology2632-88282025-01-01610.1017/qpb.2025.10002Molecular tipping points in plant cell surface H+ homeostasis and signallingKaltra Xhelilaj0Anja Thoe Fuglsang1Julien Gronnier2Michael Palmgren3https://orcid.org/0000-0002-9982-6114Center for Plant Molecular Biology (ZMBP), https://ror.org/03a1kwz48 University of Tübingen , Tübingen, GermanyDepartment of Plant and Environmental Sciences, https://ror.org/035b05819 University of Copenhagen , Frederiksberg C, DenmarkCenter for Plant Molecular Biology (ZMBP), https://ror.org/03a1kwz48 University of Tübingen , Tübingen, Germany Plant Cell Biology, School of Life Sciences, Technical University of Munich, Freising, GermanyDepartment of Plant and Environmental Sciences, https://ror.org/035b05819 University of Copenhagen , Frederiksberg C, DenmarkHydrogen, a deceptively simple element, plays crucial roles in regulating life on Earth. The concentration of hydrogen ions (H+) determines the pH of biological systems and dictates virtually all biochemical processes. The pH modulates the structure, physicochemical properties and function of most macromolecules. The plant cell surface is characterized by tremendous variations in apoplastic pH, serving as informative signals shaping plant development and its interaction with the environment. Here, we discuss the principles underlying cell surface H+ homeostasis, the molecular tipping points that regulate fast, controlled and informative changes in apoplastic pH, as well as open questions regarding the regulation of plasma membrane H+-ATPases.https://www.cambridge.org/core/product/identifier/S2632882825100027/type/journal_articleH+ homeostasisplasma membrane H+-ATPaseprotonsapoplastcell surface
spellingShingle Kaltra Xhelilaj
Anja Thoe Fuglsang
Julien Gronnier
Michael Palmgren
Molecular tipping points in plant cell surface H+ homeostasis and signalling
Quantitative Plant Biology
H+ homeostasis
plasma membrane H+-ATPase
protons
apoplast
cell surface
title Molecular tipping points in plant cell surface H+ homeostasis and signalling
title_full Molecular tipping points in plant cell surface H+ homeostasis and signalling
title_fullStr Molecular tipping points in plant cell surface H+ homeostasis and signalling
title_full_unstemmed Molecular tipping points in plant cell surface H+ homeostasis and signalling
title_short Molecular tipping points in plant cell surface H+ homeostasis and signalling
title_sort molecular tipping points in plant cell surface h homeostasis and signalling
topic H+ homeostasis
plasma membrane H+-ATPase
protons
apoplast
cell surface
url https://www.cambridge.org/core/product/identifier/S2632882825100027/type/journal_article
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AT anjathoefuglsang moleculartippingpointsinplantcellsurfacehhomeostasisandsignalling
AT juliengronnier moleculartippingpointsinplantcellsurfacehhomeostasisandsignalling
AT michaelpalmgren moleculartippingpointsinplantcellsurfacehhomeostasisandsignalling