Effect of Ketorolac on Pharmacokinetics and Pharmacodynamics of 5-Fluorouracil: In Vivo and In Vitro Study

Effect of Ketorolac on Pharmacokinetics and Pharmacodynamics of 5-Fluorouracil: In Vivo and In Vitro Study

Background. This study aimed to evaluate the impact of ketorolac on the pharmacokinetics of 5-FU and its effect on the efficacy of 5-fluorouracil (5-FU) on the HT-29 cell line. Methods. Cell culture: the HT-29 cell line was treated with different concentrations of 5-FU, ketorolac, and combination of...

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Bibliographic Details
Main Authors: Motahare Atefinezhad, Ahmadreza Moghadamnia, Seyed Parsa Eftekhar, Ali Akbar Moghadamnia, Sohrab Kazemi
Format: Article
Language:English
Published: Wiley 2022-01-01
Series:Journal of Tropical Medicine
Online Access:http://dx.doi.org/10.1155/2022/5267861
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