Effect of aminophylline on restoration of spontaneous respiration and recovery profiles during anesthesia without using muscle relaxants in patients undergoing brief gynecological procedure
Purpose of Investigation: The purpose was to evaluate the effects of aminophylline on returning of spontaneous respiration and recovery profiles during propofol-fentanyl-sevoflurane anesthesia without muscle relaxants in patients undergoing day care gynecological surgery. Materials and Methods: Sixt...
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| Format: | Article |
| Language: | English |
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IMR Press
2020-08-01
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| Series: | Clinical and Experimental Obstetrics & Gynecology |
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| Online Access: | https://www.imrpress.com/journal/CEOG/47/4/10.31083/j.ceog.2020.04.5417 |
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| author | Y.S. Jeon E.H. Jun J.H. Kim S.T. Choi J.H. In |
| author_facet | Y.S. Jeon E.H. Jun J.H. Kim S.T. Choi J.H. In |
| author_sort | Y.S. Jeon |
| collection | DOAJ |
| description | Purpose of Investigation: The purpose was to evaluate the effects of aminophylline on returning of spontaneous respiration and recovery profiles during propofol-fentanyl-sevoflurane anesthesia without muscle relaxants in patients undergoing day care gynecological surgery. Materials and Methods: Sixty-six patients were enrolled. Either aminophylline 3 mg/kg (group A) or saline (group C) was administered to each patient. Tidal volume (Vt), respiratory rate (RR), and end tidal carbon dioxide (ETCO2), apneic time, recovery time, discharge time and modified observer’s assessment of alertness/sedation scale (MOAA/S) were evaluated. Results: Apneic time and recovery time were significantly shorter in Group A than in Group C (P < 0.01). MOAA/S, tidal volume (P = 0.02) and ETCO2 (P = 0.03) were significantly improved in Group A compared with Group C. Conclusion: Aminophylline effectively reduced apneic and recovery time, thereby improving respiratory and recovery profiles during anesthesia with propofol, fentanyl, and sevoflurane in brief day care surgeries. |
| format | Article |
| id | doaj-art-e54e9d35b0184c9d8726e77a2cd305b0 |
| institution | Kabale University |
| issn | 0390-6663 |
| language | English |
| publishDate | 2020-08-01 |
| publisher | IMR Press |
| record_format | Article |
| series | Clinical and Experimental Obstetrics & Gynecology |
| spelling | doaj-art-e54e9d35b0184c9d8726e77a2cd305b02025-08-20T03:48:35ZengIMR PressClinical and Experimental Obstetrics & Gynecology0390-66632020-08-0147452452910.31083/j.ceog.2020.04.5417S0390-6663(20)00303-6Effect of aminophylline on restoration of spontaneous respiration and recovery profiles during anesthesia without using muscle relaxants in patients undergoing brief gynecological procedureY.S. Jeon0E.H. Jun1J.H. Kim2S.T. Choi3J.H. In4Department of Anesthesiology and Pain Medicine, St. Vincent's Hospital, College of Medicine, The Catholic University of Korea, Seoul, Republic of KoreaDepartment of Anesthesiology and Pain Medicine, St. Vincent's Hospital, College of Medicine, The Catholic University of Korea, Seoul, Republic of KoreaDepartment of Anesthesiology and Pain Medicine, St. Vincent's Hospital, College of Medicine, The Catholic University of Korea, Seoul, Republic of KoreaDepartment of Anesthesiology and Pain Medicine, St. Vincent's Hospital, College of Medicine, The Catholic University of Korea, Seoul, Republic of KoreaDepartment of Anesthesiology and Pain Medicine, St. Vincent's Hospital, College of Medicine, The Catholic University of Korea, Seoul, Republic of KoreaPurpose of Investigation: The purpose was to evaluate the effects of aminophylline on returning of spontaneous respiration and recovery profiles during propofol-fentanyl-sevoflurane anesthesia without muscle relaxants in patients undergoing day care gynecological surgery. Materials and Methods: Sixty-six patients were enrolled. Either aminophylline 3 mg/kg (group A) or saline (group C) was administered to each patient. Tidal volume (Vt), respiratory rate (RR), and end tidal carbon dioxide (ETCO2), apneic time, recovery time, discharge time and modified observer’s assessment of alertness/sedation scale (MOAA/S) were evaluated. Results: Apneic time and recovery time were significantly shorter in Group A than in Group C (P < 0.01). MOAA/S, tidal volume (P = 0.02) and ETCO2 (P = 0.03) were significantly improved in Group A compared with Group C. Conclusion: Aminophylline effectively reduced apneic and recovery time, thereby improving respiratory and recovery profiles during anesthesia with propofol, fentanyl, and sevoflurane in brief day care surgeries.https://www.imrpress.com/journal/CEOG/47/4/10.31083/j.ceog.2020.04.5417aminophyllinehypercapniaanesthesia recovery period |
| spellingShingle | Y.S. Jeon E.H. Jun J.H. Kim S.T. Choi J.H. In Effect of aminophylline on restoration of spontaneous respiration and recovery profiles during anesthesia without using muscle relaxants in patients undergoing brief gynecological procedure Clinical and Experimental Obstetrics & Gynecology aminophylline hypercapnia anesthesia recovery period |
| title | Effect of aminophylline on restoration of spontaneous respiration and recovery profiles during anesthesia without using muscle relaxants in patients undergoing brief gynecological procedure |
| title_full | Effect of aminophylline on restoration of spontaneous respiration and recovery profiles during anesthesia without using muscle relaxants in patients undergoing brief gynecological procedure |
| title_fullStr | Effect of aminophylline on restoration of spontaneous respiration and recovery profiles during anesthesia without using muscle relaxants in patients undergoing brief gynecological procedure |
| title_full_unstemmed | Effect of aminophylline on restoration of spontaneous respiration and recovery profiles during anesthesia without using muscle relaxants in patients undergoing brief gynecological procedure |
| title_short | Effect of aminophylline on restoration of spontaneous respiration and recovery profiles during anesthesia without using muscle relaxants in patients undergoing brief gynecological procedure |
| title_sort | effect of aminophylline on restoration of spontaneous respiration and recovery profiles during anesthesia without using muscle relaxants in patients undergoing brief gynecological procedure |
| topic | aminophylline hypercapnia anesthesia recovery period |
| url | https://www.imrpress.com/journal/CEOG/47/4/10.31083/j.ceog.2020.04.5417 |
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