Multi-omics profiling reveals distinct pathogenic mechanisms in Hunner and non-Hunner interstitial cystitis subtypes

Multi-omics profiling reveals distinct pathogenic mechanisms in Hunner and non-Hunner interstitial cystitis subtypes

Abstract Bladder Pain Syndrome/Interstitial Cystitis encompasses Hunner lesion and non-Hunner lesion (NHIC) subtypes, characterized by chronic pelvic pain and urinary symptoms. The two subtypes show distinct clinical presentations, yet their underlying mechanisms remain poorly understood. Advancemen...

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Bibliographic Details
Main Authors: Lin Zhu, Hanwei Ke, Qi Wang, Kexin Xu, Xiaofang Chen
Format: Article
Language:English
Published: Nature Portfolio 2025-07-01
Series:Scientific Reports
Subjects:
Bladder pain syndrome
Multi-omics analysis
Microbiome
Metabolomics
Transcriptomics
Disease mechanism
Online Access:https://doi.org/10.1038/s41598-025-12010-w
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https://doi.org/10.1038/s41598-025-12010-w

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