A quality by design HPLC method for cephalosporin analysis in pharmaceuticals and water samples with environmental impact assessment

A quality by design HPLC method for cephalosporin analysis in pharmaceuticals and water samples with environmental impact assessment

Abstract The present study applied a combined analytical quality-by-design and green analytical chemistry approach to develop an HPLC method for the determination of four cephalosporin pharmaceuticals in both their formulations and water samples. These drugs include ceftriaxone, cefotaxime, ceftazid...

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Bibliographic Details
Main Authors: Ali Alqahtani, Taha Alqahtani, Adel Al Fatease, Enas H. Tolba
Format: Article
Language:English
Published: Nature Portfolio 2025-01-01
Series:Scientific Reports
Subjects:
Cephalosporins
Green chemistry
HPLC
Box–Behnken
Online Access:https://doi.org/10.1038/s41598-024-84647-y
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