Craniometaphyseal Dysplasia: A review and novel oral manifestation
Craniometaphyseal Dysplasia (CMD) is a sclerosing osseous dysplasia characterised by hyperostosis of craniofacial and long bones, resulting in distortion and cranial nerve palsies.We present a case report on the management of a 63 year old female with Craniometaphyseal Dysplasia. This report describ...
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| Format: | Article |
| Language: | English |
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Elsevier
2017-05-01
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| Series: | Journal of Oral Biology and Craniofacial Research |
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| Online Access: | http://www.sciencedirect.com/science/article/pii/S2212426817300258 |
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| author | K. Martin S. Nathwani R. Bunyan |
| author_facet | K. Martin S. Nathwani R. Bunyan |
| author_sort | K. Martin |
| collection | DOAJ |
| description | Craniometaphyseal Dysplasia (CMD) is a sclerosing osseous dysplasia characterised by hyperostosis of craniofacial and long bones, resulting in distortion and cranial nerve palsies.We present a case report on the management of a 63 year old female with Craniometaphyseal Dysplasia. This report describes an additional clinical manifestation of hypercementosis, which although well recognised in other sclerosing osseous dysplasias, is not reported in the literature for Craniometaphyseal Dysplasia. We discuss established in vivo studies in mice which link the genetic mutations found in Craniometaphyseal Dysplasia to hypercementosis, and how this report describes the same manifestation in humans.This novel finding can aid the clinician in the management of patients with Craniometaphyseal Dysplasia, and complications that can arise in dentoalveolar surgery. |
| format | Article |
| id | doaj-art-e4f2d6986e674f048d2a0fd882ed88d9 |
| institution | Kabale University |
| issn | 2212-4268 |
| language | English |
| publishDate | 2017-05-01 |
| publisher | Elsevier |
| record_format | Article |
| series | Journal of Oral Biology and Craniofacial Research |
| spelling | doaj-art-e4f2d6986e674f048d2a0fd882ed88d92024-11-23T06:27:20ZengElsevierJournal of Oral Biology and Craniofacial Research2212-42682017-05-0172134136Craniometaphyseal Dysplasia: A review and novel oral manifestationK. Martin0S. Nathwani1R. Bunyan2Corresponding author.; Department of Oral and Maxillofacial Surgery, Luton and Dunstable University Hospital, Lewsey Road, Luton, LU4 0DZ, United KingdomDepartment of Oral and Maxillofacial Surgery, Luton and Dunstable University Hospital, Lewsey Road, Luton, LU4 0DZ, United KingdomDepartment of Oral and Maxillofacial Surgery, Luton and Dunstable University Hospital, Lewsey Road, Luton, LU4 0DZ, United KingdomCraniometaphyseal Dysplasia (CMD) is a sclerosing osseous dysplasia characterised by hyperostosis of craniofacial and long bones, resulting in distortion and cranial nerve palsies.We present a case report on the management of a 63 year old female with Craniometaphyseal Dysplasia. This report describes an additional clinical manifestation of hypercementosis, which although well recognised in other sclerosing osseous dysplasias, is not reported in the literature for Craniometaphyseal Dysplasia. We discuss established in vivo studies in mice which link the genetic mutations found in Craniometaphyseal Dysplasia to hypercementosis, and how this report describes the same manifestation in humans.This novel finding can aid the clinician in the management of patients with Craniometaphyseal Dysplasia, and complications that can arise in dentoalveolar surgery.http://www.sciencedirect.com/science/article/pii/S2212426817300258Craniometaphyseal DysplasiaHypercementosisSclerosing Osseous Dysplasia |
| spellingShingle | K. Martin S. Nathwani R. Bunyan Craniometaphyseal Dysplasia: A review and novel oral manifestation Journal of Oral Biology and Craniofacial Research Craniometaphyseal Dysplasia Hypercementosis Sclerosing Osseous Dysplasia |
| title | Craniometaphyseal Dysplasia: A review and novel oral manifestation |
| title_full | Craniometaphyseal Dysplasia: A review and novel oral manifestation |
| title_fullStr | Craniometaphyseal Dysplasia: A review and novel oral manifestation |
| title_full_unstemmed | Craniometaphyseal Dysplasia: A review and novel oral manifestation |
| title_short | Craniometaphyseal Dysplasia: A review and novel oral manifestation |
| title_sort | craniometaphyseal dysplasia a review and novel oral manifestation |
| topic | Craniometaphyseal Dysplasia Hypercementosis Sclerosing Osseous Dysplasia |
| url | http://www.sciencedirect.com/science/article/pii/S2212426817300258 |
| work_keys_str_mv | AT kmartin craniometaphysealdysplasiaareviewandnoveloralmanifestation AT snathwani craniometaphysealdysplasiaareviewandnoveloralmanifestation AT rbunyan craniometaphysealdysplasiaareviewandnoveloralmanifestation |