Exploring the course of functional somatic symptoms (FSS) from pre- to late adolescence and associated internalizing psychopathology – an observational cohort-study
Abstract Background Functional somatic symptoms (FSS), which commonly cannot be attributed to well-defined organic pathology, often co-occur with internalizing psychopathology and fluctuate throughout different life stages. We examined FSS courses throughout adolescence, and the association between...
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2024-07-01
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| Series: | BMC Psychiatry |
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| Online Access: | https://doi.org/10.1186/s12888-024-05937-3 |
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| author | Lina Münker Martin Køster Rimvall Lisbeth Frostholm Eva Ørnbøl Kaare Bro Wellnitz Pia Jeppesen Judith Gerarda Maria Rosmalen Charlotte Ulrikka Rask |
| author_facet | Lina Münker Martin Køster Rimvall Lisbeth Frostholm Eva Ørnbøl Kaare Bro Wellnitz Pia Jeppesen Judith Gerarda Maria Rosmalen Charlotte Ulrikka Rask |
| author_sort | Lina Münker |
| collection | DOAJ |
| description | Abstract Background Functional somatic symptoms (FSS), which commonly cannot be attributed to well-defined organic pathology, often co-occur with internalizing psychopathology and fluctuate throughout different life stages. We examined FSS courses throughout adolescence, and the association between preadolescent FSS, FSS severity and internalizing psychopathology at late adolescence. Methods Data from the Copenhagen Child Cohort (CCC2000) were utilized from assessments at ages 11–12 years (preadolescence; T0) and 16–17 years (late adolescence; T1). Self-report questionnaire and interview data on FSS, internalizing psychopathology, chronic medical conditions, and sociodemographic data from Danish national registers were available for 1285 youths. FSS courses were categorized into persistent (high FSS at T0 & T1), remission (high FSS only at T0), incident (high FSS only at T1) or no FSS (no FSS at T0 & T1). Multiple linear and multinomial logistic regressions were conducted to investigate the FSS/psychopathology association. Results 1.8% of adolescents fell into the persistent FSS course group throughout adolescence. Higher preadolescent FSS predicted FSS (b = 0.07, p < .001), anxiety (b = 0.05, p < .001) and depression (b = 0.06, p < .001) at age 16/17, even after controlling for sex, parental education, a chronic medical condition and internalizing psychopathology in preadolescence. Persistent, incident, and remittent FSS courses were associated with significantly higher mean levels of anxiety and depression compared to the reference group (no FSS). Conclusions FSS during pre- and late adolescence might increase and co-occur with anxiety and depression throughout adolescence, potentially due to shared underlying risk factors and processes. |
| format | Article |
| id | doaj-art-e4b3f5869a214d53b4b45c7bf18508b6 |
| institution | Kabale University |
| issn | 1471-244X |
| language | English |
| publishDate | 2024-07-01 |
| publisher | BMC |
| record_format | Article |
| series | BMC Psychiatry |
| spelling | doaj-art-e4b3f5869a214d53b4b45c7bf18508b62024-12-22T12:40:05ZengBMCBMC Psychiatry1471-244X2024-07-0124111210.1186/s12888-024-05937-3Exploring the course of functional somatic symptoms (FSS) from pre- to late adolescence and associated internalizing psychopathology – an observational cohort-studyLina Münker0Martin Køster Rimvall1Lisbeth Frostholm2Eva Ørnbøl3Kaare Bro Wellnitz4Pia Jeppesen5Judith Gerarda Maria Rosmalen6Charlotte Ulrikka Rask7Department of Child and Adolescent Psychiatry, Aarhus University Hospital PsychiatryDepartment of Child and Adolescent Psychiatry, Copenhagen University Hospital - Psychiatry Region ZealandDepartment of Functional Disorders and Psychosomatics, Aarhus University HospitalDepartment of Functional Disorders and Psychosomatics, Aarhus University HospitalDepartment of Functional Disorders and Psychosomatics, Aarhus University HospitalDepartment of Child and Adolescent Psychiatry, Copenhagen University Hospital - Psychiatry Region ZealandDepartments of Psychiatry and Internal medicine, University of Groningen, University Medical Center GroningenDepartment of Child and Adolescent Psychiatry, Aarhus University Hospital PsychiatryAbstract Background Functional somatic symptoms (FSS), which commonly cannot be attributed to well-defined organic pathology, often co-occur with internalizing psychopathology and fluctuate throughout different life stages. We examined FSS courses throughout adolescence, and the association between preadolescent FSS, FSS severity and internalizing psychopathology at late adolescence. Methods Data from the Copenhagen Child Cohort (CCC2000) were utilized from assessments at ages 11–12 years (preadolescence; T0) and 16–17 years (late adolescence; T1). Self-report questionnaire and interview data on FSS, internalizing psychopathology, chronic medical conditions, and sociodemographic data from Danish national registers were available for 1285 youths. FSS courses were categorized into persistent (high FSS at T0 & T1), remission (high FSS only at T0), incident (high FSS only at T1) or no FSS (no FSS at T0 & T1). Multiple linear and multinomial logistic regressions were conducted to investigate the FSS/psychopathology association. Results 1.8% of adolescents fell into the persistent FSS course group throughout adolescence. Higher preadolescent FSS predicted FSS (b = 0.07, p < .001), anxiety (b = 0.05, p < .001) and depression (b = 0.06, p < .001) at age 16/17, even after controlling for sex, parental education, a chronic medical condition and internalizing psychopathology in preadolescence. Persistent, incident, and remittent FSS courses were associated with significantly higher mean levels of anxiety and depression compared to the reference group (no FSS). Conclusions FSS during pre- and late adolescence might increase and co-occur with anxiety and depression throughout adolescence, potentially due to shared underlying risk factors and processes.https://doi.org/10.1186/s12888-024-05937-3Functional Somatic SymptomsAnxietyDepression |
| spellingShingle | Lina Münker Martin Køster Rimvall Lisbeth Frostholm Eva Ørnbøl Kaare Bro Wellnitz Pia Jeppesen Judith Gerarda Maria Rosmalen Charlotte Ulrikka Rask Exploring the course of functional somatic symptoms (FSS) from pre- to late adolescence and associated internalizing psychopathology – an observational cohort-study BMC Psychiatry Functional Somatic Symptoms Anxiety Depression |
| title | Exploring the course of functional somatic symptoms (FSS) from pre- to late adolescence and associated internalizing psychopathology – an observational cohort-study |
| title_full | Exploring the course of functional somatic symptoms (FSS) from pre- to late adolescence and associated internalizing psychopathology – an observational cohort-study |
| title_fullStr | Exploring the course of functional somatic symptoms (FSS) from pre- to late adolescence and associated internalizing psychopathology – an observational cohort-study |
| title_full_unstemmed | Exploring the course of functional somatic symptoms (FSS) from pre- to late adolescence and associated internalizing psychopathology – an observational cohort-study |
| title_short | Exploring the course of functional somatic symptoms (FSS) from pre- to late adolescence and associated internalizing psychopathology – an observational cohort-study |
| title_sort | exploring the course of functional somatic symptoms fss from pre to late adolescence and associated internalizing psychopathology an observational cohort study |
| topic | Functional Somatic Symptoms Anxiety Depression |
| url | https://doi.org/10.1186/s12888-024-05937-3 |
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