Surgical regenerative methods for peri-implantitis treatment: A systematic review and meta-analysis
Background. The purpose of this study was to review the literature on the efficacy of different surgical regenerative methods for peri-implantitis treatment. Methods. A preliminary search was conducted in seven electronic databases. The studies included in the analysis implemented surgical regenerat...
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| Format: | Article |
| Language: | English |
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Tabriz University of Medical Sciences
2024-11-01
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| Series: | Journal of Advanced Periodontology and Implant Dentistry |
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| Online Access: | https://japid.tbzmed.ac.ir/PDF/japid-16-144.pdf |
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| author | Soheil Shahbazi Saharnaz Esmaeili Armin Shirvani Reza Amid Mahdi Kadkhodazadeh |
| author_facet | Soheil Shahbazi Saharnaz Esmaeili Armin Shirvani Reza Amid Mahdi Kadkhodazadeh |
| author_sort | Soheil Shahbazi |
| collection | DOAJ |
| description | Background. The purpose of this study was to review the literature on the efficacy of different surgical regenerative methods for peri-implantitis treatment. Methods. A preliminary search was conducted in seven electronic databases. The studies included in the analysis implemented surgical regenerative treatment in at least one study group. Baseline and follow-up values for bleeding on probing (BoP), pocket depth (PD), plaque index (PI), bone level (BL), and bone gain (BG) were extracted. The standardized mean difference (SMD) was calculated using Cohen’s d or Hedges’ g, and a random-effects-restricted maximum likelihood (REML) method was applied for the meta-analysis. Results. Fifteen studies were included in the qualitative synthesis. The meta-analysis was performed on six studies comparing regenerative techniques that involved bone grafts with those that did not. The overall effect size for using bone grafts at the one-year follow-up was 0.04 (95% CI: -0.26‒0.35; P=0.78) for BoP, -0.08 (95% CI: -0.42‒0.27; P=0.66) for PD, 0.37 (95% CI: 0.08‒0.65; P=0.01) for PI, -0.44 (95% CI: -0.84 to -0.03; P=0.03) for BL, and 0.16 (95% CI: -0.68‒1.01; P=0.70) for BG. Conclusion. Various materials have been employed for peri-implant defect filling and coverage. A bone substitute did not significantly improve BoP, PD, and BG values, while PI and BL were significantly ameliorated at one-year follow-up. However, recommending a single unified protocol as the most effective for surgical regenerative treatment of peri-implantitis was not feasible. |
| format | Article |
| id | doaj-art-e4ab5a917b99419e8c26eef9d24e72f4 |
| institution | DOAJ |
| issn | 2645-5390 |
| language | English |
| publishDate | 2024-11-01 |
| publisher | Tabriz University of Medical Sciences |
| record_format | Article |
| series | Journal of Advanced Periodontology and Implant Dentistry |
| spelling | doaj-art-e4ab5a917b99419e8c26eef9d24e72f42025-08-20T03:10:10ZengTabriz University of Medical SciencesJournal of Advanced Periodontology and Implant Dentistry2645-53902024-11-0116214415910.34172/japid.2024.013japid-3518Surgical regenerative methods for peri-implantitis treatment: A systematic review and meta-analysisSoheil Shahbazi0Saharnaz Esmaeili1Armin Shirvani2Reza Amid3Mahdi Kadkhodazadeh4Dentofacial Deformities Research Center, Research Institute of Dental Sciences, Shahid Beheshti University of Medical Sciences, Tehran, IranDentofacial Deformities Research Center, Research Institute of Dental Sciences, Shahid Beheshti University of Medical Sciences, Tehran, IranIranian Center for Endodontic Research, Research Institute of Dental Sciences, Dental School, Shahid Beheshti University of Medical Sciences, Tehran, IranDental Research Center, Research Institute of Dental Sciences, Shahid Beheshti University of Medical Sciences, Tehran, IranDepartment of Periodontics, Shahid Beheshti University of Medical Sciences, Tehran, IranBackground. The purpose of this study was to review the literature on the efficacy of different surgical regenerative methods for peri-implantitis treatment. Methods. A preliminary search was conducted in seven electronic databases. The studies included in the analysis implemented surgical regenerative treatment in at least one study group. Baseline and follow-up values for bleeding on probing (BoP), pocket depth (PD), plaque index (PI), bone level (BL), and bone gain (BG) were extracted. The standardized mean difference (SMD) was calculated using Cohen’s d or Hedges’ g, and a random-effects-restricted maximum likelihood (REML) method was applied for the meta-analysis. Results. Fifteen studies were included in the qualitative synthesis. The meta-analysis was performed on six studies comparing regenerative techniques that involved bone grafts with those that did not. The overall effect size for using bone grafts at the one-year follow-up was 0.04 (95% CI: -0.26‒0.35; P=0.78) for BoP, -0.08 (95% CI: -0.42‒0.27; P=0.66) for PD, 0.37 (95% CI: 0.08‒0.65; P=0.01) for PI, -0.44 (95% CI: -0.84 to -0.03; P=0.03) for BL, and 0.16 (95% CI: -0.68‒1.01; P=0.70) for BG. Conclusion. Various materials have been employed for peri-implant defect filling and coverage. A bone substitute did not significantly improve BoP, PD, and BG values, while PI and BL were significantly ameliorated at one-year follow-up. However, recommending a single unified protocol as the most effective for surgical regenerative treatment of peri-implantitis was not feasible.https://japid.tbzmed.ac.ir/PDF/japid-16-144.pdfbone regenerationbone substitutesperi-implantitisregenerationregenerative medicine |
| spellingShingle | Soheil Shahbazi Saharnaz Esmaeili Armin Shirvani Reza Amid Mahdi Kadkhodazadeh Surgical regenerative methods for peri-implantitis treatment: A systematic review and meta-analysis Journal of Advanced Periodontology and Implant Dentistry bone regeneration bone substitutes peri-implantitis regeneration regenerative medicine |
| title | Surgical regenerative methods for peri-implantitis treatment: A systematic review and meta-analysis |
| title_full | Surgical regenerative methods for peri-implantitis treatment: A systematic review and meta-analysis |
| title_fullStr | Surgical regenerative methods for peri-implantitis treatment: A systematic review and meta-analysis |
| title_full_unstemmed | Surgical regenerative methods for peri-implantitis treatment: A systematic review and meta-analysis |
| title_short | Surgical regenerative methods for peri-implantitis treatment: A systematic review and meta-analysis |
| title_sort | surgical regenerative methods for peri implantitis treatment a systematic review and meta analysis |
| topic | bone regeneration bone substitutes peri-implantitis regeneration regenerative medicine |
| url | https://japid.tbzmed.ac.ir/PDF/japid-16-144.pdf |
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