Durability of Stretta Radiofrequency Treatment for GERD: Results of an 8-Year Follow-Up
From June 2002 to March 2013 26 patients that underwent Stretta procedure (16 females, 10 males) reached to date an eight-year follow-up. Primary end point of the study was to verify the durability of the procedure at this time. All patients underwent clinical evaluation by upper endoscopy, oesophag...
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| Format: | Article |
| Language: | English |
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Wiley
2014-01-01
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| Series: | Gastroenterology Research and Practice |
| Online Access: | http://dx.doi.org/10.1155/2014/531907 |
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| _version_ | 1841524498267897856 |
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| author | Luca Dughera Gianluca Rotondano Maria De Cento Paola Cassolino Fabio Cisarò |
| author_facet | Luca Dughera Gianluca Rotondano Maria De Cento Paola Cassolino Fabio Cisarò |
| author_sort | Luca Dughera |
| collection | DOAJ |
| description | From June 2002 to March 2013 26 patients that underwent Stretta procedure (16 females, 10 males) reached to date an eight-year follow-up. Primary end point of the study was to verify the durability of the procedure at this time. All patients underwent clinical evaluation by upper endoscopy, oesophageal pressure, and pH studies. For each patient 8-year data were compared to those recorded at baseline and at 4 years. There was a significant decrease in both heartburn and GERD HRQL scores at 4 years (P=0.001) and at 8 years (P=0.003) as well as a significant increase of QoL scores at each control time (mental SF-36 and physical SF-36, P=0.001). After 4 and 8 years, 21 patients (80.7%, P=0.0001) and 20 patients (76.9%, P=0.0001) were completely off PPIs. Median LES pressure did not show significant amelioration at 4 and 8 years and mean oesophageal acid exposure significantly improved at 4 years (P=0.001) but returned to baseline values after 8 years. This further follow-up study of ours from four to eight years confirms that RF energy delivery for GERD provides durable improvement in symptoms and in quality of life and reduces antireflux drugs consumption. |
| format | Article |
| id | doaj-art-e4a64ecd5c4d4bf9903d6e24cbd879e9 |
| institution | Kabale University |
| issn | 1687-6121 1687-630X |
| language | English |
| publishDate | 2014-01-01 |
| publisher | Wiley |
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| series | Gastroenterology Research and Practice |
| spelling | doaj-art-e4a64ecd5c4d4bf9903d6e24cbd879e92025-02-03T05:53:06ZengWileyGastroenterology Research and Practice1687-61211687-630X2014-01-01201410.1155/2014/531907531907Durability of Stretta Radiofrequency Treatment for GERD: Results of an 8-Year Follow-UpLuca Dughera0Gianluca Rotondano1Maria De Cento2Paola Cassolino3Fabio Cisarò4Digestive Motility and Endoscopy, Department of Medicine, Città della Salute e della Scienza, Via Genova, 10121 Turin, ItalyGastroenterology and Digestive Endoscopy, Ospedale Maresca, Torre del Greco, Via Montedoro, 80059 Naples, ItalyAnesthesiology, Department of Surgery, Città della Salute e della Scienza, Via Genova, 10121 Turin, ItalyEmergency Surgery, Department of Emergency, Città della Salute e della Scienza, Via Genova, 10121 Turin, ItalyPediatric Gastroenterology, Department of Medicine, Città della Salute e della Scienza, Via Genova, 10121 Turin, ItalyFrom June 2002 to March 2013 26 patients that underwent Stretta procedure (16 females, 10 males) reached to date an eight-year follow-up. Primary end point of the study was to verify the durability of the procedure at this time. All patients underwent clinical evaluation by upper endoscopy, oesophageal pressure, and pH studies. For each patient 8-year data were compared to those recorded at baseline and at 4 years. There was a significant decrease in both heartburn and GERD HRQL scores at 4 years (P=0.001) and at 8 years (P=0.003) as well as a significant increase of QoL scores at each control time (mental SF-36 and physical SF-36, P=0.001). After 4 and 8 years, 21 patients (80.7%, P=0.0001) and 20 patients (76.9%, P=0.0001) were completely off PPIs. Median LES pressure did not show significant amelioration at 4 and 8 years and mean oesophageal acid exposure significantly improved at 4 years (P=0.001) but returned to baseline values after 8 years. This further follow-up study of ours from four to eight years confirms that RF energy delivery for GERD provides durable improvement in symptoms and in quality of life and reduces antireflux drugs consumption.http://dx.doi.org/10.1155/2014/531907 |
| spellingShingle | Luca Dughera Gianluca Rotondano Maria De Cento Paola Cassolino Fabio Cisarò Durability of Stretta Radiofrequency Treatment for GERD: Results of an 8-Year Follow-Up Gastroenterology Research and Practice |
| title | Durability of Stretta Radiofrequency Treatment for GERD: Results of an 8-Year Follow-Up |
| title_full | Durability of Stretta Radiofrequency Treatment for GERD: Results of an 8-Year Follow-Up |
| title_fullStr | Durability of Stretta Radiofrequency Treatment for GERD: Results of an 8-Year Follow-Up |
| title_full_unstemmed | Durability of Stretta Radiofrequency Treatment for GERD: Results of an 8-Year Follow-Up |
| title_short | Durability of Stretta Radiofrequency Treatment for GERD: Results of an 8-Year Follow-Up |
| title_sort | durability of stretta radiofrequency treatment for gerd results of an 8 year follow up |
| url | http://dx.doi.org/10.1155/2014/531907 |
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