Connecting the dots to find the missing link in oral carcinoma

Transformation of an oral potentially malignant lesion to frank carcinoma can be considered a continuum due to the interplay of variables related to the host and environmental carcinogen exposure. Tumor populations should not be viewed as isolated cells but comprehended with the micro-environment. T...

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Main Author: Yash P. Merchant, MDS, FRCS (UK)
Format: Article
Language:English
Published: Elsevier 2023-09-01
Series:Oral Oncology Reports
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S277290602300064X
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author Yash P. Merchant, MDS, FRCS (UK)
author_facet Yash P. Merchant, MDS, FRCS (UK)
author_sort Yash P. Merchant, MDS, FRCS (UK)
collection DOAJ
description Transformation of an oral potentially malignant lesion to frank carcinoma can be considered a continuum due to the interplay of variables related to the host and environmental carcinogen exposure. Tumor populations should not be viewed as isolated cells but comprehended with the micro-environment. The seed and soil theory certainly needs revisiting.
format Article
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institution Kabale University
issn 2772-9060
language English
publishDate 2023-09-01
publisher Elsevier
record_format Article
series Oral Oncology Reports
spelling doaj-art-e4953e2941b54b259ffe24a9f028aded2024-11-23T06:32:25ZengElsevierOral Oncology Reports2772-90602023-09-017100074Connecting the dots to find the missing link in oral carcinomaYash P. Merchant, MDS, FRCS (UK)0Department of Oral and Maxillofacial Surgery, Dr. D. Y. Patil Dental College and Hospital, Dr. D. Y. Patil Vidyapeeth, Sant Tukaram Nagar, Pimpri, Pune 411018 Maharashtra, India; Department of Oral and Maxillofacial Surgery, Dr. D. Y. Patil Dental College and Hospital, Dr. D. Y. Patil Vidyapeeth, Sant Tukaram Nagar, Pimpri, Pune, Maharashtra, IndiaTransformation of an oral potentially malignant lesion to frank carcinoma can be considered a continuum due to the interplay of variables related to the host and environmental carcinogen exposure. Tumor populations should not be viewed as isolated cells but comprehended with the micro-environment. The seed and soil theory certainly needs revisiting.http://www.sciencedirect.com/science/article/pii/S277290602300064XTumor microenvironmentStromaOral carcinomaTIME
spellingShingle Yash P. Merchant, MDS, FRCS (UK)
Connecting the dots to find the missing link in oral carcinoma
Oral Oncology Reports
Tumor microenvironment
Stroma
Oral carcinoma
TIME
title Connecting the dots to find the missing link in oral carcinoma
title_full Connecting the dots to find the missing link in oral carcinoma
title_fullStr Connecting the dots to find the missing link in oral carcinoma
title_full_unstemmed Connecting the dots to find the missing link in oral carcinoma
title_short Connecting the dots to find the missing link in oral carcinoma
title_sort connecting the dots to find the missing link in oral carcinoma
topic Tumor microenvironment
Stroma
Oral carcinoma
TIME
url http://www.sciencedirect.com/science/article/pii/S277290602300064X
work_keys_str_mv AT yashpmerchantmdsfrcsuk connectingthedotstofindthemissinglinkinoralcarcinoma