Identification of a Cryptic Bacterial Promoter in Mouse (mdr1a) P-Glycoprotein cDNA.

Identification of a Cryptic Bacterial Promoter in Mouse (mdr1a) P-Glycoprotein cDNA.

The efflux transporter P-glycoprotein (P-gp) is an important mediator of various pharmacokinetic parameters, being expressed at numerous physiological barriers and also in multidrug-resistant cancer cells. Molecular cloning of homologous cDNAs is an important tool for the characterization of functio...

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Main Authors: Kristen M Pluchino, Dominic Esposito, Janna K Moen, Matthew D Hall, James P Madigan, Suneet Shukla, Lauren V Procter, Vanessa E Wall, Thomas D Schneider, Ian Pringle, Suresh V Ambudkar, Deborah R Gill, Steven C Hyde, Michael M Gottesman
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2015-01-01
Series:PLoS ONE
Online Access:https://doi.org/10.1371/journal.pone.0136396
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