Research progress on phosphodiesterase 4 inhibitors in the treatment of palmoplantar pustulosis

Research progress on phosphodiesterase 4 inhibitors in the treatment of palmoplantar pustulosis

Palmoplantar pustulosis (PPP) is a chronic recurrent inflammatory skin disease. Existing therapeutic methods cannot meet the demand by patients. Phosphodiesterase-4 (PDE-4) is a key enzyme involved in the balance of immunocytes. It acts as a downstream mediator in the signaling pathways of a variety...

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Bibliographic Details
Main Authors: YAO Xinyi, Gao Wenli, LI Juan, ZHANG Junling
Format: Article
Language:zho
Published: editoiral office of Journal of Diagnosis and Therapy on Dermato-venereology 2024-11-01
Series:Pifu-xingbing zhenliaoxue zazhi
Subjects:
palmoplantar pustulosis
pde-4 inhibitor
apremilast
crisaborole
Online Access:http://pfxbzlx.gdvdc.com/EN/10.3969/j.issn.1674-8468.2024.11.011
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