Gut microbial bile and amino acid metabolism associate with peanut oral immunotherapy failure

Gut microbial bile and amino acid metabolism associate with peanut oral immunotherapy failure

Abstract Peanut Oral Immunotherapy (POIT) holds promise for remission of peanut allergy, though treatment is protracted and successful in only a subset of patients. Because the gut microbiome has been linked to food allergy, we sought to identify fecal predictors of POIT efficacy and mechanistic ins...

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Bibliographic Details
Main Authors: Mustafa Özçam, Din L. Lin, Chhedi L. Gupta, Allison Li, J. Carlos Gomez, Lisa M. Wheatley, Carolyn H. Baloh, Srinath Sanda, Stacie M. Jones, Susan V. Lynch
Format: Article
Language:English
Published: Nature Portfolio 2025-07-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-025-61161-x
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