Plasmodium falciparum with pfhrp2 and pfhrp3 gene deletions in asymptomatic malaria infections in the Lake Victoria region, Kenya

Plasmodium falciparum with pfhrp2 and pfhrp3 gene deletions in asymptomatic malaria infections in the Lake Victoria region, Kenya

Abstract Malaria rapid diagnostic tests (RDTs) targeting the Plasmodium falciparum histidine-rich protein 2 (PfHRP2) are widely used to diagnose P. falciparum infection. However, reports of P. falciparum strains lacking PfHRP2 and the structurally similar PfHRP3 have raised concerns about the utilit...

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Bibliographic Details
Main Authors: Takatsugu Okai, Chim W. Chan, Achyut KC, Protus Omondi, Kelvin Musyoka, James Kongere, Wataru Kagaya, Gordon Okomo, Bernard N. Kanoi, Yasutoshi Kido, Jesse Gitaka, Akira Kaneko
Format: Article
Language:English
Published: BMC 2024-12-01
Series:Tropical Medicine and Health
Subjects:
Malaria
Plasmodium falciparum
Rapid diagnostic tests (RDTs)
pfhrp2
pfhrp3
Gene deletions
Online Access:https://doi.org/10.1186/s41182-024-00664-7
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