Disability and Patient-Reported Satisfaction in Women with Idiopathic Intracranial Hypertension: A Comparative Study of Venous Sinus Stenting and Medical Management

Objective: Patients with chronic idiopathic intracranial hypertension (IIH) commonly experience a high level of disability and low satisfaction with medical treatment. We aim to evaluate long-term functional improvement and patient satisfaction in IIH patients with similar symptoms by comparing veno...

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Main Authors: Ortal Buhbut, Hadas Ben Assayag, Sapir Aharoni-Bar, Maor Epstein, Erez Tsumi, Tamir Regev, Anna Bunin, Asaf Honig, Bar O. Kotaro, Gal Ben Arie, Anat Horev
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Language:English
Published: MDPI AG 2024-11-01
Series:Diagnostics
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Online Access:https://www.mdpi.com/2075-4418/14/22/2572
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author Ortal Buhbut
Hadas Ben Assayag
Sapir Aharoni-Bar
Maor Epstein
Erez Tsumi
Tamir Regev
Anna Bunin
Asaf Honig
Bar O. Kotaro
Gal Ben Arie
Anat Horev
author_facet Ortal Buhbut
Hadas Ben Assayag
Sapir Aharoni-Bar
Maor Epstein
Erez Tsumi
Tamir Regev
Anna Bunin
Asaf Honig
Bar O. Kotaro
Gal Ben Arie
Anat Horev
author_sort Ortal Buhbut
collection DOAJ
description Objective: Patients with chronic idiopathic intracranial hypertension (IIH) commonly experience a high level of disability and low satisfaction with medical treatment. We aim to evaluate long-term functional improvement and patient satisfaction in IIH patients with similar symptoms by comparing venous sinus stenting (VSS) to standard medical therapy. Methods: We conducted a cross-sectional questionnaire study of 111 IIH patients, comparing 37 adult female patients who underwent venous sinus stenting with 74 patients treated medically. Propensity score matching was used to balance age and presence of papilledema at presentation between groups. Headache-related disability was evaluated using the Migraine Disability Assessment Scale (MIDAS), while general function and treatment satisfaction were assessed using custom questionnaires. Electronic medical records and the results of imaging upon diagnosis were reviewed retrospectively. Results: The stented group reported significantly better outcomes in physical well-being (median 4.0 vs. 1.0, <i>p</i> < 0.001), task completion (4.0 vs. 1.0, <i>p</i> < 0.001), work/school persistence (5.0 vs. 1.0, <i>p</i> < 0.001), and mental well-being (4.0 vs. 1.0, <i>p</i> < 0.001). Additionally, the stented group had a lower proportion of patients with severe MIDAS (MIDAS > 4, 24.3% vs. 47.9%, <i>p</i> = 0.017). Logistic regression suggested venous stenting as a protective factor against severe MIDAS scores (OR = 0.174, <i>p</i> = 0.004). Conclusion: Cerebral venous stenting in patients with IIH is associated with lower disability and higher patient satisfaction from medical treatment compared to those treated with medications only. These findings suggest that venous sinus stenting may be a valuable treatment option for selected IIH patients. However, larger prospective studies are needed to further validate our results.
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spelling doaj-art-e37e3ba35ca04e4ebf3f3bcc1d2e640b2024-11-26T17:59:57ZengMDPI AGDiagnostics2075-44182024-11-011422257210.3390/diagnostics14222572Disability and Patient-Reported Satisfaction in Women with Idiopathic Intracranial Hypertension: A Comparative Study of Venous Sinus Stenting and Medical ManagementOrtal Buhbut0Hadas Ben Assayag1Sapir Aharoni-Bar2Maor Epstein3Erez Tsumi4Tamir Regev5Anna Bunin6Asaf Honig7Bar O. Kotaro8Gal Ben Arie9Anat Horev10Department of Ophthalmology, Soroka University Medical Center, Ben-Gurion University of the Negev, Beer Sheva 8453227, IsraelFaculty of Medicine, Tel Aviv University, Tel Aviv 69978, IsraelBen-Gurion Medical School, Soroka University Medical Center, Beer Sheva 8453227, IsraelFaculty of Health Sciences, Ben-Gurion University of the Negev, Beer Sheva 8410501, IsraelDepartment of Ophthalmology, Soroka University Medical Center, Ben-Gurion University of the Negev, Beer Sheva 8453227, IsraelDepartment of Ophthalmology, Soroka University Medical Center, Ben-Gurion University of the Negev, Beer Sheva 8453227, IsraelDepartment of Ophthalmology, Soroka University Medical Center, Ben-Gurion University of the Negev, Beer Sheva 8453227, IsraelDepartment of Neurology, Soroka University Medical Center, Ben-Gurion University of the Negev, Beer Sheva 8453227, IsraelMedical School, Faculty of Health, Palacky University, 77900 Olomouc, Czech RepublicDepartment of Diagnostic Imaging, Soroka University Medical Center, Ben-Gurion University of the Negev, Beer Sheva 8410501, IsraelDepartment of Neurology, Soroka University Medical Center, Ben-Gurion University of the Negev, Beer Sheva 8453227, IsraelObjective: Patients with chronic idiopathic intracranial hypertension (IIH) commonly experience a high level of disability and low satisfaction with medical treatment. We aim to evaluate long-term functional improvement and patient satisfaction in IIH patients with similar symptoms by comparing venous sinus stenting (VSS) to standard medical therapy. Methods: We conducted a cross-sectional questionnaire study of 111 IIH patients, comparing 37 adult female patients who underwent venous sinus stenting with 74 patients treated medically. Propensity score matching was used to balance age and presence of papilledema at presentation between groups. Headache-related disability was evaluated using the Migraine Disability Assessment Scale (MIDAS), while general function and treatment satisfaction were assessed using custom questionnaires. Electronic medical records and the results of imaging upon diagnosis were reviewed retrospectively. Results: The stented group reported significantly better outcomes in physical well-being (median 4.0 vs. 1.0, <i>p</i> < 0.001), task completion (4.0 vs. 1.0, <i>p</i> < 0.001), work/school persistence (5.0 vs. 1.0, <i>p</i> < 0.001), and mental well-being (4.0 vs. 1.0, <i>p</i> < 0.001). Additionally, the stented group had a lower proportion of patients with severe MIDAS (MIDAS > 4, 24.3% vs. 47.9%, <i>p</i> = 0.017). Logistic regression suggested venous stenting as a protective factor against severe MIDAS scores (OR = 0.174, <i>p</i> = 0.004). Conclusion: Cerebral venous stenting in patients with IIH is associated with lower disability and higher patient satisfaction from medical treatment compared to those treated with medications only. These findings suggest that venous sinus stenting may be a valuable treatment option for selected IIH patients. However, larger prospective studies are needed to further validate our results.https://www.mdpi.com/2075-4418/14/22/2572carbonic anhydrase inhibitorsheadacheidiopathic intracranial hypertensiontransverse sinus stentingquality of lifequestionnaire
spellingShingle Ortal Buhbut
Hadas Ben Assayag
Sapir Aharoni-Bar
Maor Epstein
Erez Tsumi
Tamir Regev
Anna Bunin
Asaf Honig
Bar O. Kotaro
Gal Ben Arie
Anat Horev
Disability and Patient-Reported Satisfaction in Women with Idiopathic Intracranial Hypertension: A Comparative Study of Venous Sinus Stenting and Medical Management
Diagnostics
carbonic anhydrase inhibitors
headache
idiopathic intracranial hypertension
transverse sinus stenting
quality of life
questionnaire
title Disability and Patient-Reported Satisfaction in Women with Idiopathic Intracranial Hypertension: A Comparative Study of Venous Sinus Stenting and Medical Management
title_full Disability and Patient-Reported Satisfaction in Women with Idiopathic Intracranial Hypertension: A Comparative Study of Venous Sinus Stenting and Medical Management
title_fullStr Disability and Patient-Reported Satisfaction in Women with Idiopathic Intracranial Hypertension: A Comparative Study of Venous Sinus Stenting and Medical Management
title_full_unstemmed Disability and Patient-Reported Satisfaction in Women with Idiopathic Intracranial Hypertension: A Comparative Study of Venous Sinus Stenting and Medical Management
title_short Disability and Patient-Reported Satisfaction in Women with Idiopathic Intracranial Hypertension: A Comparative Study of Venous Sinus Stenting and Medical Management
title_sort disability and patient reported satisfaction in women with idiopathic intracranial hypertension a comparative study of venous sinus stenting and medical management
topic carbonic anhydrase inhibitors
headache
idiopathic intracranial hypertension
transverse sinus stenting
quality of life
questionnaire
url https://www.mdpi.com/2075-4418/14/22/2572
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