A multiplexed high throughput screening assay using flow cytometry identifies glycolytic molecular probes in bloodstream form Trypanosoma brucei

A multiplexed high throughput screening assay using flow cytometry identifies glycolytic molecular probes in bloodstream form Trypanosoma brucei

Kinetoplastid organisms, including Trypanosoma brucei, are a significant health burden in many tropical and semitropical countries. Much of their metabolism is poorly understood. To better study kinetoplastid metabolism, chemical probes that inhibit kinetoplastid enzymes are needed. To discover chem...

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Bibliographic Details
Main Authors:	Daniel H. Call, John Asafo Adjei, Ryan Pilgrim, James W. Jeong, E. Vance Willis, Ronald A. Zegarra, Nicholas L. Tapia, Madalyn Osterhaus, Jacob A. Vance, Charles M. Voyton, James A. Call, Sabrina S. Pizarro, James C. Morris, Kenneth A. Christensen
Format:	Article
Language:	English
Published:	Elsevier 2024-12-01
Series:	International Journal for Parasitology: Drugs and Drug Resistance
Subjects:	Flow cytometry High-throughput screen Biosensor Glycolysis Trypanosoma brucei Metabolism
Online Access:	http://www.sciencedirect.com/science/article/pii/S2211320724000381
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