A multiplexed high throughput screening assay using flow cytometry identifies glycolytic molecular probes in bloodstream form Trypanosoma brucei

A multiplexed high throughput screening assay using flow cytometry identifies glycolytic molecular probes in bloodstream form Trypanosoma brucei

Kinetoplastid organisms, including Trypanosoma brucei, are a significant health burden in many tropical and semitropical countries. Much of their metabolism is poorly understood. To better study kinetoplastid metabolism, chemical probes that inhibit kinetoplastid enzymes are needed. To discover chem...

Full description

Saved in:
Bibliographic Details
Main Authors: Daniel H. Call, John Asafo Adjei, Ryan Pilgrim, James W. Jeong, E. Vance Willis, Ronald A. Zegarra, Nicholas L. Tapia, Madalyn Osterhaus, Jacob A. Vance, Charles M. Voyton, James A. Call, Sabrina S. Pizarro, James C. Morris, Kenneth A. Christensen
Format: Article
Language:English
Published: Elsevier 2024-12-01
Series:International Journal for Parasitology: Drugs and Drug Resistance
Subjects:
Flow cytometry
High-throughput screen
Biosensor
Glycolysis
Trypanosoma brucei
Metabolism
Online Access:http://www.sciencedirect.com/science/article/pii/S2211320724000381
Tags: Add Tag
No Tags, Be the first to tag this record!

Internet

http://www.sciencedirect.com/science/article/pii/S2211320724000381

Similar Items