A meta‐analysis of the effects of black soldier fly meal on fish immune response and antioxidant capacity

Black soldier fly (BSF) meal possesses a balanced nutritional profile, making it a promising substitute for fishmeal. Several studies have been conducted to investigate the effects of replacing fishmeal with BSF meal on fish immune response and antioxidant capacity. However, considering the varying...

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Main Authors: Yizhi Xiao, Lezhao Zhu, Renhao Liang, Jiequan Su, Junqi Yang, Xinyi Cao, Yao Lu, Yiyi Yu, Junjie Hu
Format: Article
Language:English
Published: Elsevier 2024-12-01
Series:Comparative Immunology Reports
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Online Access:http://www.sciencedirect.com/science/article/pii/S2950311624000296
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author Yizhi Xiao
Lezhao Zhu
Renhao Liang
Jiequan Su
Junqi Yang
Xinyi Cao
Yao Lu
Yiyi Yu
Junjie Hu
author_facet Yizhi Xiao
Lezhao Zhu
Renhao Liang
Jiequan Su
Junqi Yang
Xinyi Cao
Yao Lu
Yiyi Yu
Junjie Hu
author_sort Yizhi Xiao
collection DOAJ
description Black soldier fly (BSF) meal possesses a balanced nutritional profile, making it a promising substitute for fishmeal. Several studies have been conducted to investigate the effects of replacing fishmeal with BSF meal on fish immune response and antioxidant capacity. However, considering the varying effects of BSF meal on different fish species demonstrated in earlier studies, a meta-analysis study was imperative to determine the efficacy of BSF meal in aquafeed. This meta-analysis examined 38 studies on finfish. Subgroup analysis and meta-regression were conducted to investigate the source of heterogeneity in the immunostimulant and antioxidant efficacy of BSF meal. Categorical variables used in subgroup analysis included the BSF development stage (larvae versus prepupae or pupae), BSF processing method (full-fat versus defatted), and fish dietary habits. Two continuous variables were evaluated for meta-regression analysis: dietary BSF inclusion level and treatment duration. The datasets were assessed for publication bias using funnel plots and Egger's test with the Pustejovsky–Rodgers Approach. The results revealed that BSF meal influences immune performance and antioxidant ability. Subgroup analysis indicated that different BSF development stages significantly influence the immunostimulant and antioxidant efficacy of BSF meals, with BSF prepupae or pupae outperforming BSF larvae. In terms of processing, full-fat BSF was superior to defatted BSF. Furthermore, BSF meal demonstrated the highest efficacy in omnivorous fishes. Meta-regression outcomes revealed that a higher concentration of BSF meal may inhibit immune response and antioxidant ability and that treatment duration exerts little impact. In conclusion, the present meta-analysis demonstrated that BSF is a promising ingredient in aquafeed to improve fish immune response and antioxidant capacity.
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series Comparative Immunology Reports
spelling doaj-art-e341152fefc94948a421c6b7b327f0a32024-12-18T08:56:01ZengElsevierComparative Immunology Reports2950-31162024-12-017200162A meta‐analysis of the effects of black soldier fly meal on fish immune response and antioxidant capacityYizhi Xiao0Lezhao Zhu1Renhao Liang2Jiequan Su3Junqi Yang4Xinyi Cao5Yao Lu6Yiyi Yu7Junjie Hu8Key Laboratory of Conservation and Application in Biodiversity of South China, School of Life Sciences, Guangzhou University, Guangzhou, ChinaKey Laboratory of Conservation and Application in Biodiversity of South China, School of Life Sciences, Guangzhou University, Guangzhou, ChinaKey Laboratory of Conservation and Application in Biodiversity of South China, School of Life Sciences, Guangzhou University, Guangzhou, ChinaKey Laboratory of Conservation and Application in Biodiversity of South China, School of Life Sciences, Guangzhou University, Guangzhou, ChinaKey Laboratory of Conservation and Application in Biodiversity of South China, School of Life Sciences, Guangzhou University, Guangzhou, ChinaKey Laboratory of Conservation and Application in Biodiversity of South China, School of Life Sciences, Guangzhou University, Guangzhou, ChinaKey Laboratory of Conservation and Application in Biodiversity of South China, School of Life Sciences, Guangzhou University, Guangzhou, ChinaKey Laboratory of Conservation and Application in Biodiversity of South China, School of Life Sciences, Guangzhou University, Guangzhou, ChinaCorresponding author.; Key Laboratory of Conservation and Application in Biodiversity of South China, School of Life Sciences, Guangzhou University, Guangzhou, ChinaBlack soldier fly (BSF) meal possesses a balanced nutritional profile, making it a promising substitute for fishmeal. Several studies have been conducted to investigate the effects of replacing fishmeal with BSF meal on fish immune response and antioxidant capacity. However, considering the varying effects of BSF meal on different fish species demonstrated in earlier studies, a meta-analysis study was imperative to determine the efficacy of BSF meal in aquafeed. This meta-analysis examined 38 studies on finfish. Subgroup analysis and meta-regression were conducted to investigate the source of heterogeneity in the immunostimulant and antioxidant efficacy of BSF meal. Categorical variables used in subgroup analysis included the BSF development stage (larvae versus prepupae or pupae), BSF processing method (full-fat versus defatted), and fish dietary habits. Two continuous variables were evaluated for meta-regression analysis: dietary BSF inclusion level and treatment duration. The datasets were assessed for publication bias using funnel plots and Egger's test with the Pustejovsky–Rodgers Approach. The results revealed that BSF meal influences immune performance and antioxidant ability. Subgroup analysis indicated that different BSF development stages significantly influence the immunostimulant and antioxidant efficacy of BSF meals, with BSF prepupae or pupae outperforming BSF larvae. In terms of processing, full-fat BSF was superior to defatted BSF. Furthermore, BSF meal demonstrated the highest efficacy in omnivorous fishes. Meta-regression outcomes revealed that a higher concentration of BSF meal may inhibit immune response and antioxidant ability and that treatment duration exerts little impact. In conclusion, the present meta-analysis demonstrated that BSF is a promising ingredient in aquafeed to improve fish immune response and antioxidant capacity.http://www.sciencedirect.com/science/article/pii/S2950311624000296Fishmeal replacementMeta-analysisAquafeedSubgroup analysisMeta-regression
spellingShingle Yizhi Xiao
Lezhao Zhu
Renhao Liang
Jiequan Su
Junqi Yang
Xinyi Cao
Yao Lu
Yiyi Yu
Junjie Hu
A meta‐analysis of the effects of black soldier fly meal on fish immune response and antioxidant capacity
Comparative Immunology Reports
Fishmeal replacement
Meta-analysis
Aquafeed
Subgroup analysis
Meta-regression
title A meta‐analysis of the effects of black soldier fly meal on fish immune response and antioxidant capacity
title_full A meta‐analysis of the effects of black soldier fly meal on fish immune response and antioxidant capacity
title_fullStr A meta‐analysis of the effects of black soldier fly meal on fish immune response and antioxidant capacity
title_full_unstemmed A meta‐analysis of the effects of black soldier fly meal on fish immune response and antioxidant capacity
title_short A meta‐analysis of the effects of black soldier fly meal on fish immune response and antioxidant capacity
title_sort meta analysis of the effects of black soldier fly meal on fish immune response and antioxidant capacity
topic Fishmeal replacement
Meta-analysis
Aquafeed
Subgroup analysis
Meta-regression
url http://www.sciencedirect.com/science/article/pii/S2950311624000296
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