Non-pharmacological interventions to improve the patient experience of colonoscopy under moderate or no sedation: a systematic review protocol

Introduction The patient experience is a critical dimension of colonoscopy quality. Sedative and analgesic drugs are commonly used to improve the patient experience of colonoscopy, with predominant regimens being deep sedation, typically achieved with propofol, and moderate sedation, typically achie...

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Main Authors: Nancy N Baxter, Jill Tinmouth, Diego Llovet, Teruko Kishibe, Colin Sue-Chue-Lam, Matthew Castelo
Format: Article
Language:English
Published: BMJ Publishing Group 2020-09-01
Series:BMJ Open
Online Access:https://bmjopen.bmj.com/content/10/9/e038621.full
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author Nancy N Baxter
Jill Tinmouth
Diego Llovet
Teruko Kishibe
Colin Sue-Chue-Lam
Matthew Castelo
author_facet Nancy N Baxter
Jill Tinmouth
Diego Llovet
Teruko Kishibe
Colin Sue-Chue-Lam
Matthew Castelo
author_sort Nancy N Baxter
collection DOAJ
description Introduction The patient experience is a critical dimension of colonoscopy quality. Sedative and analgesic drugs are commonly used to improve the patient experience of colonoscopy, with predominant regimens being deep sedation, typically achieved with propofol, and moderate sedation, typically achieved with an opioid and a benzodiazepine. However, non-pharmacological interventions exist that may be used to improve patient experience. Furthermore, by identifying non-pharmacological interventions to increase the quality of patient experience under moderate sedation, jurisdictions facing rising use of deep sedation for colonoscopy and its significant associated costs may be better able to encourage patients and clinicians to adopt moderate sedation. Advancing either of these aims requires synthesising the evidence and raising awareness around these non-pharmacological interventions to improve the patient experience of colonoscopy.Methods and analysis A systematic review will be conducted that searches multiple electronic databases from inception until 2020 to identify randomised controlled trials evaluating what, if any, non-pharmacological interventions are effective compared with placebo or usual care for improving the patient experience of routine colonoscopy under moderate or no sedation. Two reviewers will independently perform a three-stage screening process and extract all study data using piloted forms. Study quality will be assessed using the Cochrane Risk of Bias Tool V.2.0. Where multiple studies evaluate a single intervention, evidence will be quantitatively synthesised using pairwise meta-analysis, otherwise narrative syntheses will be undertaken.Ethics and dissemination This is a review of existing literature not requiring ethics approval. The review findings will be included in future efforts to develop an implementation strategy to reduce the use of deep sedation for routine colonoscopy. They will also be published in a peer-reviewed journal, presented at conferences and contribute to a doctoral thesis.PROSPERO registration number CRD42020173906.
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spelling doaj-art-e32527cb9a0e44a6b8e3d5336acfab452025-01-08T03:20:10ZengBMJ Publishing GroupBMJ Open2044-60552020-09-0110910.1136/bmjopen-2020-038621Non-pharmacological interventions to improve the patient experience of colonoscopy under moderate or no sedation: a systematic review protocolNancy N Baxter0Jill Tinmouth1Diego Llovet2Teruko Kishibe3Colin Sue-Chue-Lam4Matthew Castelo56 Faculty of Medicine and Health, University of Sydney, Sydney, New South Wales, Australia2 University of Toronto Institute of Health Policy Management and Evaluation, Toronto, Ontario, CanadaCancer Care Ontario, Toronto, Ontario, Canada4 Library Services, St Michael`s Hospital, Toronto, Ontario, CanadaDepartment of Surgery, University of Toronto, Toronto, Ontario, CanadaInstitute of Health Policy, Management and Evaluation, University of Toronto, Toronto, Ontario, CanadaIntroduction The patient experience is a critical dimension of colonoscopy quality. Sedative and analgesic drugs are commonly used to improve the patient experience of colonoscopy, with predominant regimens being deep sedation, typically achieved with propofol, and moderate sedation, typically achieved with an opioid and a benzodiazepine. However, non-pharmacological interventions exist that may be used to improve patient experience. Furthermore, by identifying non-pharmacological interventions to increase the quality of patient experience under moderate sedation, jurisdictions facing rising use of deep sedation for colonoscopy and its significant associated costs may be better able to encourage patients and clinicians to adopt moderate sedation. Advancing either of these aims requires synthesising the evidence and raising awareness around these non-pharmacological interventions to improve the patient experience of colonoscopy.Methods and analysis A systematic review will be conducted that searches multiple electronic databases from inception until 2020 to identify randomised controlled trials evaluating what, if any, non-pharmacological interventions are effective compared with placebo or usual care for improving the patient experience of routine colonoscopy under moderate or no sedation. Two reviewers will independently perform a three-stage screening process and extract all study data using piloted forms. Study quality will be assessed using the Cochrane Risk of Bias Tool V.2.0. Where multiple studies evaluate a single intervention, evidence will be quantitatively synthesised using pairwise meta-analysis, otherwise narrative syntheses will be undertaken.Ethics and dissemination This is a review of existing literature not requiring ethics approval. The review findings will be included in future efforts to develop an implementation strategy to reduce the use of deep sedation for routine colonoscopy. They will also be published in a peer-reviewed journal, presented at conferences and contribute to a doctoral thesis.PROSPERO registration number CRD42020173906.https://bmjopen.bmj.com/content/10/9/e038621.full
spellingShingle Nancy N Baxter
Jill Tinmouth
Diego Llovet
Teruko Kishibe
Colin Sue-Chue-Lam
Matthew Castelo
Non-pharmacological interventions to improve the patient experience of colonoscopy under moderate or no sedation: a systematic review protocol
BMJ Open
title Non-pharmacological interventions to improve the patient experience of colonoscopy under moderate or no sedation: a systematic review protocol
title_full Non-pharmacological interventions to improve the patient experience of colonoscopy under moderate or no sedation: a systematic review protocol
title_fullStr Non-pharmacological interventions to improve the patient experience of colonoscopy under moderate or no sedation: a systematic review protocol
title_full_unstemmed Non-pharmacological interventions to improve the patient experience of colonoscopy under moderate or no sedation: a systematic review protocol
title_short Non-pharmacological interventions to improve the patient experience of colonoscopy under moderate or no sedation: a systematic review protocol
title_sort non pharmacological interventions to improve the patient experience of colonoscopy under moderate or no sedation a systematic review protocol
url https://bmjopen.bmj.com/content/10/9/e038621.full
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