Catheter – related thrombosis in cancer patients: Data from the registry of thrombosis and nEoplasia of SEOM (TESEO)
Background: Catheter related thrombosis (CRT) is the most frequent non-infectious complication associated with central venous access devices (CVAD), with a reported incidence between 13 % and 66 % in symptomatic and asymptomatic patients, respectively, with several factors influencing its developmen...
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Elsevier
2024-12-01
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| Series: | Thrombosis Update |
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| Online Access: | http://www.sciencedirect.com/science/article/pii/S2666572724000336 |
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| author | Francisco José Pelegrín Mateo Teresa Quintanar Verdúguez Dialina Brilhante Asia Ferrández Arias Alejandra Romano Cardozo Eva Martínez de Castro José Muñoz Langa Elena Brozos Vázquez María Vallamayor Delgado Berta Obispo Portero Enrique Gallardo José Rubio Pérez Isaura Fernández Pérez Ignacio García Escobar Silvia García Adrián José Antonio Santiago Crespo Lola Rodríguez-Nogueira Gretel Benítez López Paula Jimenez-Fonseca Andrés Muñoz Martín |
| author_facet | Francisco José Pelegrín Mateo Teresa Quintanar Verdúguez Dialina Brilhante Asia Ferrández Arias Alejandra Romano Cardozo Eva Martínez de Castro José Muñoz Langa Elena Brozos Vázquez María Vallamayor Delgado Berta Obispo Portero Enrique Gallardo José Rubio Pérez Isaura Fernández Pérez Ignacio García Escobar Silvia García Adrián José Antonio Santiago Crespo Lola Rodríguez-Nogueira Gretel Benítez López Paula Jimenez-Fonseca Andrés Muñoz Martín |
| author_sort | Francisco José Pelegrín Mateo |
| collection | DOAJ |
| description | Background: Catheter related thrombosis (CRT) is the most frequent non-infectious complication associated with central venous access devices (CVAD), with a reported incidence between 13 % and 66 % in symptomatic and asymptomatic patients, respectively, with several factors influencing its development. Methods: CRT events recorded in TESEO, an international, multicentric, and prospective cancer-associated thrombosis registry were assessed. Descriptive analyses were conducted. Results: Between July 2018 and December 2023, 2,567 patients were included in TESEO. Of these, 245 patients developed CRT and were included in this analysis. Mean age was 60.5 years (SD 12.3). Peripherally inserted central catheters (PICC) were present in 42.1%, totally implanted ports (PORT) in 40.9% while 17% had missing data. The most common reported comorbidities were arterial hypertension (28.6%) and dyslipidemia (28.2%). Other thromboembolism associated risk factors were present in ≤10% of patients.Venous thromboembolism (VTE) related symptoms occurred in 70.2% of cases at presentation. Pulmonary embolism (PE) was present in 6.5%, being clinically suspected in 56.2% of cases. The diagnosis was mainly unilateral (81.3%) and 50% were central. Arterial and venous rethrombosis was present in 0.8% and 4.9% of cases respectively. Minor bleeding episodes occurred in 2.5% of cases, while major/clinically relevant episodes were present in 3.6%. Conclusions: Usual VTE associated risk factors were infrequent in the TESEO registry population. CRT was symptomatic in most cases, with reduced complication rates after treatment. |
| format | Article |
| id | doaj-art-e2d8bbb35b2c406a9e5fc2acad1c4d44 |
| institution | Kabale University |
| issn | 2666-5727 |
| language | English |
| publishDate | 2024-12-01 |
| publisher | Elsevier |
| record_format | Article |
| series | Thrombosis Update |
| spelling | doaj-art-e2d8bbb35b2c406a9e5fc2acad1c4d442024-12-19T11:00:52ZengElsevierThrombosis Update2666-57272024-12-0117100191Catheter – related thrombosis in cancer patients: Data from the registry of thrombosis and nEoplasia of SEOM (TESEO)Francisco José Pelegrín Mateo0Teresa Quintanar Verdúguez1Dialina Brilhante2Asia Ferrández Arias3Alejandra Romano Cardozo4Eva Martínez de Castro5José Muñoz Langa6Elena Brozos Vázquez7María Vallamayor Delgado8Berta Obispo Portero9Enrique Gallardo10José Rubio Pérez11Isaura Fernández Pérez12Ignacio García Escobar13Silvia García Adrián14José Antonio Santiago Crespo15Lola Rodríguez-Nogueira16Gretel Benítez López17Paula Jimenez-Fonseca18Andrés Muñoz Martín19Medical Oncology Department, Hospital Universitario de la Santa Creu i Sant Pau, Barcelona, Spain; Corresponding author.Medical Oncology Department, Hospital General Universitario de Elche, Elche, SpainInstituto Português de Oncologia de Lisboa Francisco Gentil, Lisboa, PortugalMedical Oncology Department, Hospital General Universitario de Elche, Elche, SpainMedical Oncology Department, Hospital Universitario de la Santa Creu i Sant Pau, Barcelona, Spain; Medicine Department, Universidad Autònoma de Barcelona, Barcelona, SpainMedical Oncology Department, Hospital Universitario Marqués de Valdecilla, IDIVAL, Santander, SpainMedical Oncology Department, Hospital Clínico Universitario de Valencia, SpainMedical Oncology Department, Complejo Hospitalario de A Coruña, A Coruña, SpainMedical Oncology Department, Hospital Universitario Ramón y Cajal, Madrid, SpainMedical Oncology Department, Hospital Universitario Infanta Leonor, Madrid, SpainMedical Oncology Department, Parc Taulí Hospital Universitari, Institut d’Investigació i Innovació Parc Taulí (I3PT-CERCA), Sabadell, Spain; Medicine Department, Universidad Autònoma de Barcelona, Barcelona, SpainMedical Oncology Department, Fundación Jiménez Díaz, Madrid, SpainMedical Oncology Department, EOXI Vigo- Hospital Universitario Álvaro Cunqueiro, Vigo, SpainMedical Oncology Department, Hospital General Universitario de Ciudad Real, Ciudad Real, SpainMedical Oncology Department, Hospital Universitario de Móstoles, Madrid, SpainMedical Oncology Department, Hospital General Universitario, Virgen de la Luz, Cuenca, SpainMedical Oncology Department, Hospital Universitario 12 de octubre, Madrid, SpainMedical Oncology Department, Hospital Universitario Insular de Gran Canaria, Las Palmas, SpainMedical Oncology Department, Hospital Universitario Central de Asturias, ISPA, Oviedo, SpainMedical Oncology Department, Hospital General Universitario Gregorio Marañón, Universidad Complutense, Madrid, SpainBackground: Catheter related thrombosis (CRT) is the most frequent non-infectious complication associated with central venous access devices (CVAD), with a reported incidence between 13 % and 66 % in symptomatic and asymptomatic patients, respectively, with several factors influencing its development. Methods: CRT events recorded in TESEO, an international, multicentric, and prospective cancer-associated thrombosis registry were assessed. Descriptive analyses were conducted. Results: Between July 2018 and December 2023, 2,567 patients were included in TESEO. Of these, 245 patients developed CRT and were included in this analysis. Mean age was 60.5 years (SD 12.3). Peripherally inserted central catheters (PICC) were present in 42.1%, totally implanted ports (PORT) in 40.9% while 17% had missing data. The most common reported comorbidities were arterial hypertension (28.6%) and dyslipidemia (28.2%). Other thromboembolism associated risk factors were present in ≤10% of patients.Venous thromboembolism (VTE) related symptoms occurred in 70.2% of cases at presentation. Pulmonary embolism (PE) was present in 6.5%, being clinically suspected in 56.2% of cases. The diagnosis was mainly unilateral (81.3%) and 50% were central. Arterial and venous rethrombosis was present in 0.8% and 4.9% of cases respectively. Minor bleeding episodes occurred in 2.5% of cases, while major/clinically relevant episodes were present in 3.6%. Conclusions: Usual VTE associated risk factors were infrequent in the TESEO registry population. CRT was symptomatic in most cases, with reduced complication rates after treatment.http://www.sciencedirect.com/science/article/pii/S2666572724000336Catheter-related thrombosisPulmonary embolismDeep vein thrombosisRethrombosisBleeding |
| spellingShingle | Francisco José Pelegrín Mateo Teresa Quintanar Verdúguez Dialina Brilhante Asia Ferrández Arias Alejandra Romano Cardozo Eva Martínez de Castro José Muñoz Langa Elena Brozos Vázquez María Vallamayor Delgado Berta Obispo Portero Enrique Gallardo José Rubio Pérez Isaura Fernández Pérez Ignacio García Escobar Silvia García Adrián José Antonio Santiago Crespo Lola Rodríguez-Nogueira Gretel Benítez López Paula Jimenez-Fonseca Andrés Muñoz Martín Catheter – related thrombosis in cancer patients: Data from the registry of thrombosis and nEoplasia of SEOM (TESEO) Thrombosis Update Catheter-related thrombosis Pulmonary embolism Deep vein thrombosis Rethrombosis Bleeding |
| title | Catheter – related thrombosis in cancer patients: Data from the registry of thrombosis and nEoplasia of SEOM (TESEO) |
| title_full | Catheter – related thrombosis in cancer patients: Data from the registry of thrombosis and nEoplasia of SEOM (TESEO) |
| title_fullStr | Catheter – related thrombosis in cancer patients: Data from the registry of thrombosis and nEoplasia of SEOM (TESEO) |
| title_full_unstemmed | Catheter – related thrombosis in cancer patients: Data from the registry of thrombosis and nEoplasia of SEOM (TESEO) |
| title_short | Catheter – related thrombosis in cancer patients: Data from the registry of thrombosis and nEoplasia of SEOM (TESEO) |
| title_sort | catheter related thrombosis in cancer patients data from the registry of thrombosis and neoplasia of seom teseo |
| topic | Catheter-related thrombosis Pulmonary embolism Deep vein thrombosis Rethrombosis Bleeding |
| url | http://www.sciencedirect.com/science/article/pii/S2666572724000336 |
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