A comprehensive investigation of PRMT5 in the prognosis and ion channel features of lung cancer

A comprehensive investigation of PRMT5 in the prognosis and ion channel features of lung cancer

The increasing incidence and mortality associated with lung cancer (LC) is a significant global health challenge. The underlying mechanisms contributing to LC remain inadequately understood. However, emerging evidence suggests that the epigenetic modifier protein arginine methyltransferase 5 (PRMT5)...

Full description

Saved in:

Bibliographic Details
Main Authors:	Yan Wang, Daifang Chu, Haichao Li, Jiangjiang Fan, Ximing Zhu, Yulong Ma, Zhongping Gu, Nianlin Xie, Pengyu Jing
Format:	Article
Language:	English
Published:	Frontiers Media S.A. 2024-11-01
Series:	Frontiers in Oncology
Subjects:	lung cancer PRMT5 prognosis epigenetics ion channel genes
Online Access:	https://www.frontiersin.org/articles/10.3389/fonc.2024.1478672/full
Tags:	Add Tag No Tags, Be the first to tag this record!

Similar Items

PRMT6 promotes colorectal cancer progress via activating MYC signaling
by: Xin Zhang, et al.
Published: (2025-01-01)

Targeting PRMT5 through PROTAC for the treatment of triple-negative breast cancer
by: Yaxun Guo, et al.
Published: (2024-11-01)

PRMT1‐mediated arginine methylation promotes YAP activation and hepatocellular carcinoma proliferation
by: Jian Yu, et al.
Published: (2024-12-01)

Prmt5 is essential for intestinal stem cell maintenance and homeostasis
by: Li Yang, et al.
Published: (2025-02-01)

PRMT5 Inhibitor EPZ015666 Decreases the Viability and Encystment of <i>Entamoeba invadens</i>
by: Rigoberto Ortiz-Hernández, et al.
Published: (2024-12-01)

TNG908 is a brain-penetrant, MTA-cooperative PRMT5 inhibitor developed for the treatment of MTAP-deleted cancers
by: Kimberly J. Briggs, et al.
Published: (2025-02-01)

Inhibitory Effect of PRMT5/MTA Inhibitor on MTAP‐Deficient Glioma May Be Influenced by Surrounding Normal Cells
by: Yunjie Wang, et al.
Published: (2024-12-01)

PRMT1 Promotes the Self‐renewal of Leukemia Stem Cells by Regulating Protein Synthesis
by: Min Zhou, et al.
Published: (2025-02-01)

TBL2 Promotes Tumorigenesis via PRMT5/WDR77‐Mediated AKT Activation in Breast Cancer
by: Xiuqing Lu, et al.
Published: (2024-12-01)

Discovery of novel PRMT1 inhibitors: a combined approach using AI classification model and traditional virtual screening
by: Jungan Zhang, et al.
Published: (2025-01-01)

Emerging roles of mechanosensitive ion channels in ventilator induced lung injury: a systematic review
by: Gang Liu, et al.
Published: (2024-11-01)

PRMT5 promotes ovarian cancer growth through enhancing Warburg effect by methylating ENO1
by: Fei Xie, et al.
Published: (2023-04-01)

Ion channel-mediated mitochondrial volume regulation and its relationship with mitochondrial dynamics
by: Yujia Zhuang, et al.
Published: (2024-12-01)

Prmt1-mediated histone H4R3me2a methylation regulates the proliferation, migration and invasion of laryngeal cancer cells by affecting the expression level of NCOA5
by: Linlu Li, et al.
Published: (2024-12-01)

Effects of Ion Channeling and Co-Implants on Ion Ranges and Damage in Si: Studies With PL, SRP, SIMS and MC Models
by: Michael I. Current, et al.
Published: (2024-01-01)

The role and mechanism of vascular wall cell ion channels in vascular fibrosis remodeling
by: Xiaolin Zhang, et al.
Published: (2024-12-01)

Novel insights into voltage-gated ion channels: Translational breakthroughs in medical oncology
by: Minas Sakellakis, et al.
Published: (2024-12-01)

Phytochemical-based therapeutics from traditional eastern medicine: analgesic effects and ion channel modulation
by: Sung Eun Kim, et al.
Published: (2025-01-01)

Voltage-Gated Ion Channel Compensatory Effect in DEE: Implications for Future Therapies
by: Khadijeh Shabani, et al.
Published: (2024-10-01)

Impact of chemoradiotherapy for first primary lung cancer on the prognosis and re-chemoradiotherapy sensitivity of second primary lung cancer
by: Zhe Chen, et al.
Published: (2025-01-01)

PRMT5 inhibition has a potent anti-tumor activity against adenoid cystic carcinoma of salivary glands
by: Vasudha Mishra, et al.
Published: (2025-01-01)

Ion channels research in hPSC-RPE cells: bridging benchwork to clinical applications
by: Ping Xu, et al.
Published: (2024-11-01)

HEG1 as a novel potential biomarker for the prognosis of lung adenocarcinoma
by: Xin Zou, et al.
Published: (2023-02-01)

Advancements in Targeting Ion Channels for the Treatment of Neurodegenerative Diseases
by: Yuxuan Li, et al.
Published: (2024-10-01)

The Significant Therapeutic Effects of Chinese Scorpion: Modern Scientific Exploration of Ion Channels
by: Yueyuan Zheng, et al.
Published: (2024-12-01)

A Novel Lysosome‐Related Gene Signature Predicts Lung Cancer Prognosis: A Bioinformatics‐Driven Study
by: Wei Ye, et al.
Published: (2024-12-01)

Recent advances on the structure and the function relationships of the TRPV4 ion channel
by: Raúl Sánchez-Hernández, et al.
Published: (2024-12-01)

Multiomic machine learning on lactylation for molecular typing and prognosis of lung adenocarcinoma
by: Mengmeng Hua, et al.
Published: (2025-01-01)

Comprehensive analysis of telomere and aging-related signature for predicting prognosis and immunotherapy response in lung adenocarcinoma
by: Zhe Ye, et al.
Published: (2025-01-01)

The association between Chlamydia pneumoniae infection and prognosis in lung cancer patients: a prospective study
by: Maolin Liu, et al.
Published: (2025-01-01)

Application and research progress of synthetic lethality in the development of anticancer therapeutic drugs
by: Xiaoliang Gong, et al.
Published: (2024-11-01)

Li-ion transport in two-dimensional nanofluidic membranes
by: Gyu Won Kim, et al.
Published: (2024-12-01)

Assessing Prognosis: Factors Influencing Outcomes in Hospitalized Lung Cancer
by: Jesús Peña-López, et al.
Published: (2024-12-01)

Ion channels in acinar cells in acute pancreatitis: crosstalk of calcium, iron, and copper signals
by: Hanli Wang, et al.
Published: (2024-11-01)

Do KATP channels have a role in immunity?
by: Stefan Feske, et al.
Published: (2024-11-01)

Editorial: Role of ion channels and metabotropic receptors in oligodendrogliogenesis: novel targets for demyelinating pathologies
by: Federica Cherchi, et al.
Published: (2024-11-01)

Ion channel classification through machine learning and protein language model embeddings
by: Ghazikhani Hamed, et al.
Published: (2024-11-01)

The role of PCBP1 in carbon ion-induced ferroptosis and inhibition of lung adenocarcinoma proliferation
by: Zhenchao Kang, et al.
Published: (2025-01-01)

The Unique Roles of Ion Channels in Pluripotent Stem Cells in Response to Biological Stimuli
by: Taku Kaitsuka
Published: (2024-12-01)

The prognosis and adjuvant chemotherapy in KRAS mutation patients with stage I lung adenocarcinoma
by: Shangshang Ma, et al.
Published: (2024-12-01)