Multiplexed Lectin-PAINT super-resolution microscopy enables cell glycotyping

Abstract Glycosylation profoundly influences cellular function, yet deciphering its intricate patterns remains a formidable challenge. Current techniques often compromise sensitivity, multiplexing, or the ability to capture in-situ cell-to-cell variations. To address these limitations, we introduce...

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Bibliographic Details
Main Authors: Marrit M. E. Tholen, Roger Riera, Cristina Izquierdo-Lozano, Lorenzo Albertazzi
Format: Article
Language:English
Published: Nature Portfolio 2025-02-01
Series:Communications Biology
Online Access:https://doi.org/10.1038/s42003-025-07626-7
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