3D virtual histology of rodent and primate cochleae with multi-scale phase-contrast X-ray tomography

3D virtual histology of rodent and primate cochleae with multi-scale phase-contrast X-ray tomography

Abstract Multi-scale X-ray phase contrast tomography (XPCT) enables three-dimensional (3D), non-destructive imaging of intact small animal cochlea and apical cochlear turns. Here we report on post-mortem imaging of excised non-human primate and rodent cochleae at different $${\upmu }$$ -CT and nano-...

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Bibliographic Details
Main Authors: Jannis J. Schaeper, Christoph A. Kampshoff, Bettina J. Wolf, Lennart Roos, Susann Michanski, Torben Ruhwedel, Marina Eckermann, Alexander Meyer, Marcus Jeschke, Carolin Wichmann, Tobias Moser, Tim Salditt
Format: Article
Language:English
Published: Nature Portfolio 2025-03-01
Series:Scientific Reports
Subjects:
Cochlea imaging
X-ray tomography
Synchrotron radiation
Micro-CT
Phase contrast
Spiral ganglion neurons
Online Access:https://doi.org/10.1038/s41598-025-89431-0
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