Extra Domain B Fibronectin as a Target for Near-Infrared Fluorescence Imaging of Rheumatoid Arthritis Affected Joints In Vivo

Extra Domain B Fibronectin as a Target for Near-Infrared Fluorescence Imaging of Rheumatoid Arthritis Affected Joints In Vivo

We investigated a molecular imaging approach for the detection of collagen-induced arthritis in rats by targeting the extra domain B (ED-B) of the extracellular matrix protein fibronectin. ED-B is a highly conserved domain (identical in human and rats) that is produced by alternative splicing during...

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Main Authors: Sonja Vollmer, Axel Vater, Kai Licha, Ines Gemeinhardt, Ole Gemeinhardt, Jan Voigt, Bernd Ebert, Jörg Schnorr, Matthias Taupitz, Rainer Macdonald, Michael Schirner
Format: Article
Language:English
Published: SAGE Publishing 2009-11-01
Series:Molecular Imaging
Online Access:https://doi.org/10.2310/7290.2009.00030
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