Infections among adults hospitalized in intensive care after the 2023 earthquake in the southeastern part of Türkiye: a multi-center observational study
Abstract Background Scarce evidence is available on the epidemiology of microbiologically proven clinical infections in patients admitted to the intensive care unit (ICU) after a great earthquake. The main aim of this study was to assess clinical infections and microbiological features in patients a...
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BMC
2025-01-01
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| Series: | BMC Infectious Diseases |
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| Online Access: | https://doi.org/10.1186/s12879-024-10416-x |
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| author | Esat Kivanc Kaya Burcin Halacli Goksel Guven Mehmet Yildirim Asir Eren Seven Emin Gemcioglu Meltem Simsek Begum Erdemir Sullu Recep Civan Yuksel Ahmet Safa Kaynar Aliye Esmaoglu Banu Kilicaslan Seda Banu Akinci Kursat Gundogan Ebru Ortac Ersoy Jordi Rello Arzu Topeli On behalf of the Turkish Intensive Care Studies-Network (TRICS-Net) |
| author_facet | Esat Kivanc Kaya Burcin Halacli Goksel Guven Mehmet Yildirim Asir Eren Seven Emin Gemcioglu Meltem Simsek Begum Erdemir Sullu Recep Civan Yuksel Ahmet Safa Kaynar Aliye Esmaoglu Banu Kilicaslan Seda Banu Akinci Kursat Gundogan Ebru Ortac Ersoy Jordi Rello Arzu Topeli On behalf of the Turkish Intensive Care Studies-Network (TRICS-Net) |
| author_sort | Esat Kivanc Kaya |
| collection | DOAJ |
| description | Abstract Background Scarce evidence is available on the epidemiology of microbiologically proven clinical infections in patients admitted to the intensive care unit (ICU) after a great earthquake. The main aim of this study was to assess clinical infections and microbiological features in patients admitted to the ICU following the 2023 earthquake in the southeastern region of Türkiye with a focus on the timing of culture positivity during their ICU stay. The secondary objectives included determining antibiotic susceptibility patterns, identifying the types of antibiotics administered upon ICU admission, evaluating the appropriateness of antibiotic usage, assessing patient outcomes, and identifying factors that influence microbiologically confirmed clinical infections. Methods A retrospective, multicenter, observational study was conducted on adult earthquake victims admitted to the ICU after the 2023 earthquake in southeastern Türkiye. Patients were categorized into four groups on the basis of culture positivity timing at the 72-hour breakpoint and clinical characteristics were compared among these groups. Factors influencing microbiologically proven clinical infections were also analysed. Results A total of 107 earthquake-affected adults (58 females and 49 males, median [IQR] age: 37 [27–57] years) were analysed. Infection was present in 50.5% of the patients, predominantly with multidrug-resistant pathogens. Amputation (OR 5.30) and intermittent hemodialysis (OR 2.98) before ICU admission were independent predictors of infection. Conclusions This study demonstrated that half of the patients admitted to the ICU with earthquake-related injuries had microbiologically proven clinical infections, highlighting the early presence of multidrug-resistant pathogens. |
| format | Article |
| id | doaj-art-e22f2e2fa7d54a97a72c988af1765f1e |
| institution | Kabale University |
| issn | 1471-2334 |
| language | English |
| publishDate | 2025-01-01 |
| publisher | BMC |
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| series | BMC Infectious Diseases |
| spelling | doaj-art-e22f2e2fa7d54a97a72c988af1765f1e2025-01-12T12:09:38ZengBMCBMC Infectious Diseases1471-23342025-01-0125111210.1186/s12879-024-10416-xInfections among adults hospitalized in intensive care after the 2023 earthquake in the southeastern part of Türkiye: a multi-center observational studyEsat Kivanc Kaya0Burcin Halacli1Goksel Guven2Mehmet Yildirim3Asir Eren Seven4Emin Gemcioglu5Meltem Simsek6Begum Erdemir Sullu7Recep Civan Yuksel8Ahmet Safa Kaynar9Aliye Esmaoglu10Banu Kilicaslan11Seda Banu Akinci12Kursat Gundogan13Ebru Ortac Ersoy14Jordi Rello15Arzu Topeli16On behalf of the Turkish Intensive Care Studies-Network (TRICS-Net)Department of Internal Medicine, Division of Intensive Care Medicine, Hacettepe University Faculty of MedicineDepartment of Internal Medicine, Division of Intensive Care Medicine, Hacettepe University Faculty of MedicineDepartment of Internal Medicine, Division of Intensive Care Medicine, Hacettepe University Faculty of MedicineDepartment of Internal Medicine, Division of Intensive Care Medicine, Hacettepe University Faculty of MedicineDepartment of Internal Medicine, Ministry of Health, Etlik City HospitalDepartment of Internal Medicine, Ministry of Health, Etlik City HospitalIntensive Care Unit, Ministry of Health, Etlik City HospitalDepartment of Anesthesiology and Reanimation, Division of Intensive Care Medicine, Hacettepe University Faculty of MedicineDepartment of Internal Medicine, Division of Intensive Care Medicine, Erciyes University Faculty of MedicineDepartment of Internal Medicine, Division of Intensive Care Medicine, Erciyes University Faculty of MedicineDepartment of Anesthesiology and Reanimation, Erciyes University Faculty of MedicineDepartment of Anesthesiology and Reanimation, Division of Intensive Care Medicine, Hacettepe University Faculty of MedicineDepartment of Anesthesiology and Reanimation, Division of Intensive Care Medicine, Hacettepe University Faculty of MedicineDepartment of Internal Medicine, Division of Intensive Care Medicine, Erciyes University Faculty of MedicineDepartment of Internal Medicine, Division of Intensive Care Medicine, Hacettepe University Faculty of MedicineClinical Research/Epidemiology in Pneumonia and Sepsis (CRIPS), Vall d’Hebron Research InstituteDepartment of Internal Medicine, Division of Intensive Care Medicine, Hacettepe University Faculty of MedicineAbstract Background Scarce evidence is available on the epidemiology of microbiologically proven clinical infections in patients admitted to the intensive care unit (ICU) after a great earthquake. The main aim of this study was to assess clinical infections and microbiological features in patients admitted to the ICU following the 2023 earthquake in the southeastern region of Türkiye with a focus on the timing of culture positivity during their ICU stay. The secondary objectives included determining antibiotic susceptibility patterns, identifying the types of antibiotics administered upon ICU admission, evaluating the appropriateness of antibiotic usage, assessing patient outcomes, and identifying factors that influence microbiologically confirmed clinical infections. Methods A retrospective, multicenter, observational study was conducted on adult earthquake victims admitted to the ICU after the 2023 earthquake in southeastern Türkiye. Patients were categorized into four groups on the basis of culture positivity timing at the 72-hour breakpoint and clinical characteristics were compared among these groups. Factors influencing microbiologically proven clinical infections were also analysed. Results A total of 107 earthquake-affected adults (58 females and 49 males, median [IQR] age: 37 [27–57] years) were analysed. Infection was present in 50.5% of the patients, predominantly with multidrug-resistant pathogens. Amputation (OR 5.30) and intermittent hemodialysis (OR 2.98) before ICU admission were independent predictors of infection. Conclusions This study demonstrated that half of the patients admitted to the ICU with earthquake-related injuries had microbiologically proven clinical infections, highlighting the early presence of multidrug-resistant pathogens.https://doi.org/10.1186/s12879-024-10416-xCrush syndromeInfectionAntimicrobial resistanceIneffective antibiotic treatmentCritical careCritically-ill |
| spellingShingle | Esat Kivanc Kaya Burcin Halacli Goksel Guven Mehmet Yildirim Asir Eren Seven Emin Gemcioglu Meltem Simsek Begum Erdemir Sullu Recep Civan Yuksel Ahmet Safa Kaynar Aliye Esmaoglu Banu Kilicaslan Seda Banu Akinci Kursat Gundogan Ebru Ortac Ersoy Jordi Rello Arzu Topeli On behalf of the Turkish Intensive Care Studies-Network (TRICS-Net) Infections among adults hospitalized in intensive care after the 2023 earthquake in the southeastern part of Türkiye: a multi-center observational study BMC Infectious Diseases Crush syndrome Infection Antimicrobial resistance Ineffective antibiotic treatment Critical care Critically-ill |
| title | Infections among adults hospitalized in intensive care after the 2023 earthquake in the southeastern part of Türkiye: a multi-center observational study |
| title_full | Infections among adults hospitalized in intensive care after the 2023 earthquake in the southeastern part of Türkiye: a multi-center observational study |
| title_fullStr | Infections among adults hospitalized in intensive care after the 2023 earthquake in the southeastern part of Türkiye: a multi-center observational study |
| title_full_unstemmed | Infections among adults hospitalized in intensive care after the 2023 earthquake in the southeastern part of Türkiye: a multi-center observational study |
| title_short | Infections among adults hospitalized in intensive care after the 2023 earthquake in the southeastern part of Türkiye: a multi-center observational study |
| title_sort | infections among adults hospitalized in intensive care after the 2023 earthquake in the southeastern part of turkiye a multi center observational study |
| topic | Crush syndrome Infection Antimicrobial resistance Ineffective antibiotic treatment Critical care Critically-ill |
| url | https://doi.org/10.1186/s12879-024-10416-x |
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