A panel of six immune-related mRNAs as biomarkers for tuberculosis diagnosis

A panel of six immune-related mRNAs as biomarkers for tuberculosis diagnosis

ObjectiveThis study aims to screen common immunological markers of lung tissues and blood for diagnosis of tuberculosis (TB).MethodsDifferentially expressed miRNAs (DEmRs) and mRNAs (DEGs) were obtained by whole-transcriptome sequencing profiles on 18F-FDG PET/CT high and low metabolic active region...

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Main Authors: Yutong Wei, Zilu Wen, Qinghua Xue, Lin Wang, Hui Chen, Lei Shi, Laiyi Wan, Leilei Li, Hongwei Li, Wentao Hao, Shulin Zhang, Ka-Wing Wong, Xiaoli Yu, Yanzheng Song
Format: Article
Language:English
Published: Frontiers Media S.A. 2025-03-01
Series:Frontiers in Genetics
Subjects:
tuberculosis
miRNA
immune gene signature
diagnosis
LASSO regression
Online Access:https://www.frontiersin.org/articles/10.3389/fgene.2025.1544007/full
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https://www.frontiersin.org/articles/10.3389/fgene.2025.1544007/full

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