Anti-restriction functions of injected phage proteins revealed by peeling back layers of bacterial immunity

Abstract Virus-host competition drives evolution of diverse antivirus defenses, but how they co-operate in wild bacteria and how bacteriophages circumvent host immunity remains poorly understood. Here, using a functional screening platform to systematically explore the functions of phage accessory g...

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Bibliographic Details
Main Authors: Sukrit Silas, Héloïse Carion, Kira S. Makarova, David Sanchez Godinez, Surabhi Haniyur, Lucy Volino, Wearn-Xin Yee, Andrea Fossati, Danielle Swaney, Michael Bocek, Eugene V. Koonin, Joseph Bondy-Denomy
Format: Article
Language:English
Published: Nature Portfolio 2025-08-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-025-63056-3
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