First-line combination therapy of immunotherapy plus anti-angiogenic drug for thoracic SMARCA4-deficient undifferentiated tumors in AIDS: a case report and review of the literature

First-line combination therapy of immunotherapy plus anti-angiogenic drug for thoracic SMARCA4-deficient undifferentiated tumors in AIDS: a case report and review of the literature

BackgroundThoracic SMARCA4-deficient undifferentiated tumors (SMARCA4-UT) exhibit a notably aggressive phenotype, which is associated with poor patient survival outcomes. These tumors are generally resistant to conventional cytotoxic chemotherapy, thereby limiting the availability of effective treat...

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Bibliographic Details
Main Authors: Xiaoling Wei, Xiangju Xing, Wei Yao, Changzheng Wang, Yajie Xiao, Xianzhi Du
Format: Article
Language:English
Published: Frontiers Media S.A. 2025-01-01
Series:Frontiers in Immunology
Subjects:
thoracic SMARCA4-deficient undifferentiated tumor
aids
immunotherapy
anti-angiogenic drug
lung cancer
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2024.1473578/full
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