Genotoxic effects of NDMA-contaminated ranitidine on Allium cepa cells and unveiling carcinogenic mechanisms via DFT and molecular dynamics simulation study

Abstract This study investigated the potential genotoxic and carcinogenic effects of N-nitrosodimethylamine (NDMA), a hazardous compound found in ranitidine formulations that are used to treat excessive stomach acid. The study first examined the effects of NDMA-contaminated ranitidine formulation on...

Full description

Saved in:
Bibliographic Details
Main Authors: Mst. Kusum Kaly, Md Ekhtiar Rahman, Md. Sohel Rana, Uzzal Kumar Acharjee, Khondokar Nasirujjaman
Format: Article
Language:English
Published: Nature Portfolio 2024-12-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-024-82984-6
Tags: Add Tag
No Tags, Be the first to tag this record!