Therapeutic deep eutectic solvent with saponin, optimized through response surface methodology, exert potent in vivo antimicrobial effects against Pseudomonas aeruginosa

Therapeutic deep eutectic solvent with saponin, optimized through response surface methodology, exert potent in vivo antimicrobial effects against Pseudomonas aeruginosa

Abstract Therapeutic deep eutectic solvents (THEDES) are a type of deep eutectics that can be used as active pharmaceutical ingredients (APIs) by enhancing the drug bioavailability, by increasing the solubility of APIs in aqueous solutions or by increasing their permeability through biological barri...

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Bibliographic Details
Main Authors: Ramya M. Subramani, Bhanuvalli R. Shamprasad, Narayana Shri Sanjeev Viswanathan, Saisubramanian Nagarajan, Arvind Sivasubramanian
Format: Article
Language:English
Published: Nature Portfolio 2024-11-01
Series:Scientific Reports
Subjects:
Therapeutic deep eutectic solvents
Box-Behnken- response surface methodology
Pseudomonas aeruginosa
Antibiofilm agents
Online Access:https://doi.org/10.1038/s41598-024-76993-8
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