Severe cutaneous drug toxicity following disitamab vedotin treatment for metastatic gastric cancer: a case report
BackgroundThis study reports a case of severe cutaneous toxicity in a patient with metastatic gastric cancer induced by disitamab vedotin, emphasizing the need for careful monitoring and management in such treatments.Case presentationA 71-year-old female was admitted to hospital complaining of serio...
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| Format: | Article |
| Language: | English |
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Frontiers Media S.A.
2025-01-01
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| Series: | Frontiers in Oncology |
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| Online Access: | https://www.frontiersin.org/articles/10.3389/fonc.2024.1504079/full |
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| author | Zhao Luping Cheng Zhen Li Piaopiao |
| author_facet | Zhao Luping Cheng Zhen Li Piaopiao |
| author_sort | Zhao Luping |
| collection | DOAJ |
| description | BackgroundThis study reports a case of severe cutaneous toxicity in a patient with metastatic gastric cancer induced by disitamab vedotin, emphasizing the need for careful monitoring and management in such treatments.Case presentationA 71-year-old female was admitted to hospital complaining of serious rashes following the first cycle of disitamab vedotin regimen for metastatic gastric cancer. The doctor diagnosedtoxic epidermal necrolysis (TEN) induced by the drug. The patient received high-dose methylprednisolone due to the side effects. This resulted in a gradual improvement of symptoms.ConclusionDuring the use of disitamab vedotin, patients need to be monitored for severe skin toxicity. |
| format | Article |
| id | doaj-art-e117955a0050441a958565f77a91e835 |
| institution | Kabale University |
| issn | 2234-943X |
| language | English |
| publishDate | 2025-01-01 |
| publisher | Frontiers Media S.A. |
| record_format | Article |
| series | Frontiers in Oncology |
| spelling | doaj-art-e117955a0050441a958565f77a91e8352025-01-16T11:30:17ZengFrontiers Media S.A.Frontiers in Oncology2234-943X2025-01-011410.3389/fonc.2024.15040791504079Severe cutaneous drug toxicity following disitamab vedotin treatment for metastatic gastric cancer: a case reportZhao Luping0Cheng Zhen1Li Piaopiao2Department of Pharmacy, Dongyang People’s Hospital, Dongyang, Zhejiang, ChinaDepartment of Medical Oncology, Dongyang People’s Hospital, Dongyang, Zhejiang, ChinaDepartment of Pharmacy, Dongyang People’s Hospital, Dongyang, Zhejiang, ChinaBackgroundThis study reports a case of severe cutaneous toxicity in a patient with metastatic gastric cancer induced by disitamab vedotin, emphasizing the need for careful monitoring and management in such treatments.Case presentationA 71-year-old female was admitted to hospital complaining of serious rashes following the first cycle of disitamab vedotin regimen for metastatic gastric cancer. The doctor diagnosedtoxic epidermal necrolysis (TEN) induced by the drug. The patient received high-dose methylprednisolone due to the side effects. This resulted in a gradual improvement of symptoms.ConclusionDuring the use of disitamab vedotin, patients need to be monitored for severe skin toxicity.https://www.frontiersin.org/articles/10.3389/fonc.2024.1504079/fulldisitamab vedotincase reportsevere cutaneous drug toxicityadverse effectsmetastatic gastric cancer |
| spellingShingle | Zhao Luping Cheng Zhen Li Piaopiao Severe cutaneous drug toxicity following disitamab vedotin treatment for metastatic gastric cancer: a case report Frontiers in Oncology disitamab vedotin case report severe cutaneous drug toxicity adverse effects metastatic gastric cancer |
| title | Severe cutaneous drug toxicity following disitamab vedotin treatment for metastatic gastric cancer: a case report |
| title_full | Severe cutaneous drug toxicity following disitamab vedotin treatment for metastatic gastric cancer: a case report |
| title_fullStr | Severe cutaneous drug toxicity following disitamab vedotin treatment for metastatic gastric cancer: a case report |
| title_full_unstemmed | Severe cutaneous drug toxicity following disitamab vedotin treatment for metastatic gastric cancer: a case report |
| title_short | Severe cutaneous drug toxicity following disitamab vedotin treatment for metastatic gastric cancer: a case report |
| title_sort | severe cutaneous drug toxicity following disitamab vedotin treatment for metastatic gastric cancer a case report |
| topic | disitamab vedotin case report severe cutaneous drug toxicity adverse effects metastatic gastric cancer |
| url | https://www.frontiersin.org/articles/10.3389/fonc.2024.1504079/full |
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