Ketone Esters Partially and Selectively Rescue Mitochondrial Bioenergetics After Acute Cervical Spinal Cord Injury in Rats: A Time-Course

Ketone Esters Partially and Selectively Rescue Mitochondrial Bioenergetics After Acute Cervical Spinal Cord Injury in Rats: A Time-Course

Spinal cord injury (SCI) pathology and pathophysiology can be attributed to both primary physical injury and secondary injury cascades. Secondary injury cascades involve dysregulated metabolism and energetic deficits directly linked to compromised mitochondrial bioenergetics. Rescuing mitochondrial...

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Bibliographic Details
Main Authors: Oscar Seira, HyoJoon (David) Park, Jie Liu, Michelle Poovathukaran, Kieran Clarke, Robert Boushel, Wolfram Tetzlaff
Format: Article
Language:English
Published: MDPI AG 2024-10-01
Series:Cells
Subjects:
D-β-hydroxybutyrate
metabolism
dietary treatment
respirometry
neurotrauma
Online Access:https://www.mdpi.com/2073-4409/13/21/1746
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