Leveraging AI to explore structural contexts of post-translational modifications in drug binding

Abstract Post-translational modifications (PTMs) play a crucial role in allowing cells to expand the functionality of their proteins and adaptively regulate their signaling pathways. Defects in PTMs have been linked to numerous developmental disorders and human diseases, including cancer, diabetes,...

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Bibliographic Details
Main Authors: Kirill E. Medvedev, R. Dustin Schaeffer, Nick V. Grishin
Format: Article
Language:English
Published: BMC 2025-05-01
Series:Journal of Cheminformatics
Subjects:
Online Access:https://doi.org/10.1186/s13321-025-01019-y
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