Neuro-dynamic Programming to Optimal Control of a Biotechnological Process

Dynamic programming (DP) is an elegant way to solve problems related to optimization and optimal control of processes. DP, however, has one major drawback, namely the “curse of dimensionality”. To overcome this shortcoming, an approach called neuro-dynamic programming (NDP) has been developed. This...

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Main Authors: Tatiana Ilkova, Mitko Petrov
Format: Article
Language:English
Published: Bulgarian Academy of Sciences 2024-12-01
Series:International Journal Bioautomation
Subjects:
Online Access:http://www.biomed.bas.bg/bioautomation/2024/vol_28.4/files/28.4_03.pdf
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author Tatiana Ilkova
Mitko Petrov
author_facet Tatiana Ilkova
Mitko Petrov
author_sort Tatiana Ilkova
collection DOAJ
description Dynamic programming (DP) is an elegant way to solve problems related to optimization and optimal control of processes. DP, however, has one major drawback, namely the “curse of dimensionality”. To overcome this shortcoming, an approach called neuro-dynamic programming (NDP) has been developed. This approach solves the “curse of dimensionality” problem of DP. For this purpose, a neural network is used in NDP, which ignores the poor results of the utility criterion. In this way, the time for solving the specific task is significantly shortened. In this work, an NDP algorithm is presented for the optimal control of a fed-batch biotechnological process for the production of L-lysine by the strain Brevibacterium flavum 22LD. Application of the NDP algorithm ensures maximum productivity of the L-lysine.
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publishDate 2024-12-01
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series International Journal Bioautomation
spelling doaj-art-e09f2e9b53784d9ba3e9a8068701711d2025-01-09T10:27:31ZengBulgarian Academy of SciencesInternational Journal Bioautomation1314-19021314-23212024-12-0128420522010.7546/ijba.2024.28.4.001036Neuro-dynamic Programming to Optimal Control of a Biotechnological ProcessTatiana Ilkova0Mitko PetrovFaculty of Engineering, South-West University “Neofit Rilski”, 66 Ivan Mihaylov Str., 2700 Blagoevgrad, BulgariaDynamic programming (DP) is an elegant way to solve problems related to optimization and optimal control of processes. DP, however, has one major drawback, namely the “curse of dimensionality”. To overcome this shortcoming, an approach called neuro-dynamic programming (NDP) has been developed. This approach solves the “curse of dimensionality” problem of DP. For this purpose, a neural network is used in NDP, which ignores the poor results of the utility criterion. In this way, the time for solving the specific task is significantly shortened. In this work, an NDP algorithm is presented for the optimal control of a fed-batch biotechnological process for the production of L-lysine by the strain Brevibacterium flavum 22LD. Application of the NDP algorithm ensures maximum productivity of the L-lysine.http://www.biomed.bas.bg/bioautomation/2024/vol_28.4/files/28.4_03.pdfoptimal controldynamic programmingneuro-dynamic programmingfed-batch biotechnological processesl-lysine productionbrevibacterium flavum 22ld strain
spellingShingle Tatiana Ilkova
Mitko Petrov
Neuro-dynamic Programming to Optimal Control of a Biotechnological Process
International Journal Bioautomation
optimal control
dynamic programming
neuro-dynamic programming
fed-batch biotechnological processes
l-lysine production
brevibacterium flavum 22ld strain
title Neuro-dynamic Programming to Optimal Control of a Biotechnological Process
title_full Neuro-dynamic Programming to Optimal Control of a Biotechnological Process
title_fullStr Neuro-dynamic Programming to Optimal Control of a Biotechnological Process
title_full_unstemmed Neuro-dynamic Programming to Optimal Control of a Biotechnological Process
title_short Neuro-dynamic Programming to Optimal Control of a Biotechnological Process
title_sort neuro dynamic programming to optimal control of a biotechnological process
topic optimal control
dynamic programming
neuro-dynamic programming
fed-batch biotechnological processes
l-lysine production
brevibacterium flavum 22ld strain
url http://www.biomed.bas.bg/bioautomation/2024/vol_28.4/files/28.4_03.pdf
work_keys_str_mv AT tatianailkova neurodynamicprogrammingtooptimalcontrolofabiotechnologicalprocess
AT mitkopetrov neurodynamicprogrammingtooptimalcontrolofabiotechnologicalprocess