Carboxymethyl cellulose/shellac composite loaded with pomegranate extract and jojoba oil as anti-mycotic and anti-mycotoxigenic food packaging materials
Abstract Food commodities, including mycotoxins naturally produced from toxigenic fungi (pre- or post-harvest), are particularly vulnerable to contamination. The study intended to use unique bioactive composites loaded with antimicrobial constituents for food packaging. Three composite types are bas...
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Nature Portfolio
2025-01-01
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| Online Access: | https://doi.org/10.1038/s41598-024-81933-7 |
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| author | Salah A. A. Mohamed Amr Farouk Adel G. Abdel-Razek El-Shahat Nashy Mohamed El-Sakhawy Ahmed Noah Badr |
| author_facet | Salah A. A. Mohamed Amr Farouk Adel G. Abdel-Razek El-Shahat Nashy Mohamed El-Sakhawy Ahmed Noah Badr |
| author_sort | Salah A. A. Mohamed |
| collection | DOAJ |
| description | Abstract Food commodities, including mycotoxins naturally produced from toxigenic fungi (pre- or post-harvest), are particularly vulnerable to contamination. The study intended to use unique bioactive composites loaded with antimicrobial constituents for food packaging. Three composite types are based on carboxymethyl cellulose/shellac (CMC/SH) and loaded with pomegranate extract (POE) with or without jojoba oil (JOE) at various concentrations. An enhancement was recorded for tensile strength and elongation at break and burst properties of the composites, where the results point out the amelioration of flexibility and elasticity with E9 (0.3/3 mg/mL of POE/JO). Moreover, E10 (0.3/1 of POE/JOE) content had higher phenolic and flavonoids, with significant antioxidants and the best antimicrobial and anti-mycotoxigenic activity. Six higher antimicrobial composites were chosen for corn seed coating applications in a simulated experiment of toxigenic fungal contamination, where the results recommend E10 as the best formula for packaging application. The E10 was characterized for emulsion stability, particle size, zeta potential, pH, PDI, and acidity that were recorded at 88.16 ± 2.87%, 54.81 nm, 38.74 mV, 6.34 ± 0.54, 31.12 ± 1.02, and 6.02 ± 0.34 mg/L, respectively. The in-silico study revealed that ellagic acid and hesperidin in POE extract, erucic and oleic acids in JOE, and shellac had the highest binding free energies against the vital enzymes involved in bactericidal/bacteriostatic effects and the aflatoxin bio synthetic mechanism. |
| format | Article |
| id | doaj-art-e0852eca7611480d92b229263ea45ed8 |
| institution | Kabale University |
| issn | 2045-2322 |
| language | English |
| publishDate | 2025-01-01 |
| publisher | Nature Portfolio |
| record_format | Article |
| series | Scientific Reports |
| spelling | doaj-art-e0852eca7611480d92b229263ea45ed82025-01-12T12:19:56ZengNature PortfolioScientific Reports2045-23222025-01-0115112310.1038/s41598-024-81933-7Carboxymethyl cellulose/shellac composite loaded with pomegranate extract and jojoba oil as anti-mycotic and anti-mycotoxigenic food packaging materialsSalah A. A. Mohamed0Amr Farouk1Adel G. Abdel-Razek2El-Shahat Nashy3Mohamed El-Sakhawy4Ahmed Noah Badr5Packing and Packaging Materials Department, National Research CentreChemistry of Flavor and Aroma Department, National Research CentreFats and Oils Department, National Research CentreChemical Industries Research Institute, National Research CentreCellulose & Paper Department, National Research CentreFood Toxicology and Contaminants Department, National Research CentreAbstract Food commodities, including mycotoxins naturally produced from toxigenic fungi (pre- or post-harvest), are particularly vulnerable to contamination. The study intended to use unique bioactive composites loaded with antimicrobial constituents for food packaging. Three composite types are based on carboxymethyl cellulose/shellac (CMC/SH) and loaded with pomegranate extract (POE) with or without jojoba oil (JOE) at various concentrations. An enhancement was recorded for tensile strength and elongation at break and burst properties of the composites, where the results point out the amelioration of flexibility and elasticity with E9 (0.3/3 mg/mL of POE/JO). Moreover, E10 (0.3/1 of POE/JOE) content had higher phenolic and flavonoids, with significant antioxidants and the best antimicrobial and anti-mycotoxigenic activity. Six higher antimicrobial composites were chosen for corn seed coating applications in a simulated experiment of toxigenic fungal contamination, where the results recommend E10 as the best formula for packaging application. The E10 was characterized for emulsion stability, particle size, zeta potential, pH, PDI, and acidity that were recorded at 88.16 ± 2.87%, 54.81 nm, 38.74 mV, 6.34 ± 0.54, 31.12 ± 1.02, and 6.02 ± 0.34 mg/L, respectively. The in-silico study revealed that ellagic acid and hesperidin in POE extract, erucic and oleic acids in JOE, and shellac had the highest binding free energies against the vital enzymes involved in bactericidal/bacteriostatic effects and the aflatoxin bio synthetic mechanism.https://doi.org/10.1038/s41598-024-81933-7Edible compositePomegranateJojoba oilAnti-mycotoxigenicPackaging foodMolecular docking |
| spellingShingle | Salah A. A. Mohamed Amr Farouk Adel G. Abdel-Razek El-Shahat Nashy Mohamed El-Sakhawy Ahmed Noah Badr Carboxymethyl cellulose/shellac composite loaded with pomegranate extract and jojoba oil as anti-mycotic and anti-mycotoxigenic food packaging materials Scientific Reports Edible composite Pomegranate Jojoba oil Anti-mycotoxigenic Packaging food Molecular docking |
| title | Carboxymethyl cellulose/shellac composite loaded with pomegranate extract and jojoba oil as anti-mycotic and anti-mycotoxigenic food packaging materials |
| title_full | Carboxymethyl cellulose/shellac composite loaded with pomegranate extract and jojoba oil as anti-mycotic and anti-mycotoxigenic food packaging materials |
| title_fullStr | Carboxymethyl cellulose/shellac composite loaded with pomegranate extract and jojoba oil as anti-mycotic and anti-mycotoxigenic food packaging materials |
| title_full_unstemmed | Carboxymethyl cellulose/shellac composite loaded with pomegranate extract and jojoba oil as anti-mycotic and anti-mycotoxigenic food packaging materials |
| title_short | Carboxymethyl cellulose/shellac composite loaded with pomegranate extract and jojoba oil as anti-mycotic and anti-mycotoxigenic food packaging materials |
| title_sort | carboxymethyl cellulose shellac composite loaded with pomegranate extract and jojoba oil as anti mycotic and anti mycotoxigenic food packaging materials |
| topic | Edible composite Pomegranate Jojoba oil Anti-mycotoxigenic Packaging food Molecular docking |
| url | https://doi.org/10.1038/s41598-024-81933-7 |
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