Investigating the hypotensive effect of focused ultrasound neuromodulation and barbiturate-loaded nanodroplets in healthy and hypertensive rats

Investigating the hypotensive effect of focused ultrasound neuromodulation and barbiturate-loaded nanodroplets in healthy and hypertensive rats

Background: Current strategies for reducing blood pressure (BP) are ineffective and unsafe for many patient populations, including drug-resistant hypertension and during pregnancy. Stimulating the periaqueductal grey (PAG) region has shown promise in treating drug-resistant hypertension in patients...

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Bibliographic Details
Main Authors: Harriet Lea-Banks, Neha Chauhan, Kullervo Hynynen
Format: Article
Language:English
Published: Elsevier 2024-11-01
Series:Brain Stimulation
Subjects:
Neuromodulation
Periaqueductal grey
Phase-change emulsion
Blood pressure
Cavitation
Online Access:http://www.sciencedirect.com/science/article/pii/S1935861X24001967
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