Structure of the distribution of genetic determinants of the efficacy and safety of non-steroidal anti-inflammatory drugs in the Russian population: focus on CYP2C8, PTGS1 and PTGS2

Structure of the distribution of genetic determinants of the efficacy and safety of non-steroidal anti-inflammatory drugs in the Russian population: focus on CYP2C8, PTGS1 and PTGS2

The efficacy and safety of non-steroidal anti-inflammatory drugs (NSAIDs) may be determined by the polymorphic nature of the CYP2C8, PTGS1 and PTGS2 genes.Objective: to analyze the nature of the distribution of CYP2C8*3 (rs10509681), CYP2C8*3 (rs11572080), PTGS1 (rs10306135), PTGS1 (rs12353214) and...

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Bibliographic Details
Main Authors: N. P. Denisenko, Sh. P. Abdullaev, K. A. Akmalova, Zh. A. Sozaeva, A. A. Kachanova, M. S-Kh. Sozaeva, L. Z. Bolieva, E. A. Grishina, D. A. Sychev
Format: Article
Language:Russian
Published: IMA-PRESS LLC 2022-02-01
Series:Современная ревматология
Subjects:
pharmacogenetics
ethnic groups
cyp2c8
ptgs1
ptgs2
non-steroidal anti-inflammatory drugs
Online Access:https://mrj.ima-press.net/mrj/article/view/1253
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