Clinical prognosticators and targets in the immune microenvironment of intrahepatic cholangiocarcinoma

Clinical prognosticators and targets in the immune microenvironment of intrahepatic cholangiocarcinoma

Background Intrahepatic cholangiocarcinoma (ICC) is a disease with poor prognosis and limited therapeutic options. We investigated the tumor immune microenvironment (TIME) to identify predictors of disease outcome and to explore targets for therapeutic modulation.Methods Liver tissue samples were co...

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Main Authors: Isis Lozzi, Alexander Arnold, Matthias Barone, Juliette Claire Johnson, Bruno V Sinn, Johannes Eschrich, Pimrapat Gebert, Ruonan Wang, Mengwen Hu, Linda Feldbrügge, Anja Schirmeier, Anja Reutzel-Selke, Thomas Malinka, Felix Krenzien, Wenzel Schöning, Dominik P Modest, Johann Pratschke, Igor M Sauer, Matthäus Felsenstein
Format: Article
Language:English
Published: Taylor & Francis Group 2024-12-01
Series:OncoImmunology
Subjects:
Immune cell prognosticators
immunomodulation
intrahepatic cholangiocarcinoma
tumor immune microenvironment
Online Access:https://www.tandfonline.com/doi/10.1080/2162402X.2024.2406052
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